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Mutations of Human DopamineTransporter at Tyrosine88, Aspartic Acid206, and Histidine547 Influence Basal and HIV-1 Tat‐inhibited Dopamine Transport

HIV-1 transactivator of transcription (Tat) has a great impact on the development of HIV-1 associated neurocognitive disorders through disrupting dopamine transmission. This study determined the mutational effects of human dopamine transporter (hDAT) on basal and Tat-induced inhibition of dopamine t...

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Detalles Bibliográficos
Autores principales:	Quizon, Pamela M., Yuan, Yaxia, Zhu, Yike, Zhou, Yi, Strauss, Matthew J., Sun, Wei-Lun, Zhan, Chang-Guo, Zhu, Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329121/ https://www.ncbi.nlm.nih.gov/pubmed/33537927 http://dx.doi.org/10.1007/s11481-021-09984-5

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