Poly-L-arginine promotes asthma angiogenesis through induction of FGFBP1 in airway epithelial cells via activation of the mTORC1-STAT3 pathway

Angiogenesis is a key characteristic of asthma airway remodeling. By releasing cationic granule proteins, such as major basic protein (MBP), activated eosinophils play a prominent role in asthma, but the underlying mechanisms are still not fully understood. In this study, we demonstrated that fibrob...

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Detalles Bibliográficos
Autores principales: Chen, Xu, Miao, Manli, Zhou, Meng, Chen, Jie, Li, Dapeng, Zhang, Ling, Sun, Anjiang, Guan, Minglong, Wang, Zixi, Liu, Ping, Zhang, Shengquan, Zha, Xiaojun, Fan, Xiaoyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329163/
https://www.ncbi.nlm.nih.gov/pubmed/34341336
http://dx.doi.org/10.1038/s41419-021-04055-2

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