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KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats
Currently there is no effective treatment available for osteoarthritis (OA). We have recently developed Kyoto University Substances (KUSs), ATPase inhibitors specific for valosin-containing protein (VCP), as a novel class of medicine for cellular protection. KUSs suppressed intracellular ATP depleti...
Autores principales: | Iwai, Sachiko, Ikeda, Hanako O., Mera, Hisashi, Nishitani, Kohei, Saito, Motoo, Tsujikawa, Akitaka, Kakizuka, Akira |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329178/ https://www.ncbi.nlm.nih.gov/pubmed/34341460 http://dx.doi.org/10.1038/s41598-021-95173-6 |
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