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KUS121 attenuates the progression of monosodium iodoacetate-induced osteoarthritis in rats

Currently there is no effective treatment available for osteoarthritis (OA). We have recently developed Kyoto University Substances (KUSs), ATPase inhibitors specific for valosin-containing protein (VCP), as a novel class of medicine for cellular protection. KUSs suppressed intracellular ATP depleti...

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Detalles Bibliográficos
Autores principales: Iwai, Sachiko, Ikeda, Hanako O., Mera, Hisashi, Nishitani, Kohei, Saito, Motoo, Tsujikawa, Akitaka, Kakizuka, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329178/
https://www.ncbi.nlm.nih.gov/pubmed/34341460
http://dx.doi.org/10.1038/s41598-021-95173-6

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