Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding

Importin-(Imp)β family nucleocytoplasmic transport receptors (NTRs) are supposed to bind to their cargoes through interaction between a confined interface on an NTR and a nuclear localization or export signal (NLS/NES) on a cargo. Although consensus NLS/NES sequence motifs have been defined for carg...

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Detalles Bibliográficos
Autores principales: Kimura, Makoto, Imai, Kenichiro, Morinaka, Yuriko, Hosono-Sakuma, Yoshiko, Horton, Paul, Imamoto, Naoko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329185/
https://www.ncbi.nlm.nih.gov/pubmed/34341383
http://dx.doi.org/10.1038/s41598-021-94948-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329185/
https://www.ncbi.nlm.nih.gov/pubmed/34341383
http://dx.doi.org/10.1038/s41598-021-94948-1

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