Cargando…

Distinct mutations in importin-β family nucleocytoplasmic transport receptors transportin-SR and importin-13 affect specific cargo binding

Importin-(Imp)β family nucleocytoplasmic transport receptors (NTRs) are supposed to bind to their cargoes through interaction between a confined interface on an NTR and a nuclear localization or export signal (NLS/NES) on a cargo. Although consensus NLS/NES sequence motifs have been defined for carg...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kimura, Makoto, Imai, Kenichiro, Morinaka, Yuriko, Hosono-Sakuma, Yoshiko, Horton, Paul, Imamoto, Naoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329185/ https://www.ncbi.nlm.nih.gov/pubmed/34341383 http://dx.doi.org/10.1038/s41598-021-94948-1

Ejemplares similares

Extensive cargo identification reveals distinct biological roles of the 12 importin pathways
por: Kimura, Makoto, et al.
Publicado: (2017)

Novel evidence for the nucleocytoplasmic shuttling of HIV-1 Tat by Importin13
por: Woods, Elena, et al.
Publicado: (2013)

Higher Nucleoporin-Importinβ Affinity at the Nuclear Basket Increases Nucleocytoplasmic Import
por: Azimi, Mohammad, et al.
Publicado: (2013)

Importin-β and the small guanosine triphosphatase Ran mediate chromosome loading of the human chromokinesin Kid
por: Tahara, Kiyoshi, et al.
Publicado: (2008)

Mechanical control of nuclear import by Importin-7 is regulated by its dominant cargo YAP
por: García-García, María, et al.
Publicado: (2022)

CBP-Mediated Acetylation of Importin α Mediates Calcium-Dependent Nucleocytoplasmic Transport of Selective Proteins in Drosophila Neurons
por: Cho, Jae Ho, et al.
Publicado: (2022)

Importins and exportins in cellular differentiation
por: Okada, Norihisa, et al.
Publicado: (2008)

Xenopus importin beta validates human importin beta as a cell cycle negative regulator
por: Delmar, Valerie A, et al.
Publicado: (2008)

The molecular basis for the regulation of the CBC by the importins
por: Dias, Sandra M.G., et al.
Publicado: (2009)

Increased expression of importin13 in endometriosis and endometrial carcinoma
por: Zeng, Biao, et al.
Publicado: (2012)

Increased importin 13 activity is associated with the pathogenesis of pterygium
por: Xu, Ke, et al.
Publicado: (2013)

Activin and BMP Signalling in Human Testicular Cancer Cell Lines, and a Role for the Nucleocytoplasmic Transport Protein Importin-5 in Their Crosstalk
por: Radhakrishnan, Karthika, et al.
Publicado: (2023)

Probing formation of cargo/importin-α transport complexes in plant cells using a pathogen effector
por: Wirthmueller, Lennart, et al.
Publicado: (2015)

Nuclear importin α and its physiological importance
por: Miyamoto, Yoichi, et al.
Publicado: (2012)

Importin-beta-like nuclear transport receptors
por: Ström, Anne-Christine, et al.
Publicado: (2001)

Stimulated nuclear import by β-like importins
por: Flores, Karen, et al.
Publicado: (2013)

Importins and Exportins Regulating Allergic Immune Responses
por: Aggarwal, Ankita, et al.
Publicado: (2014)

Co-translational binding of importins to nascent proteins
por: Seidel, Maximilian, et al.
Publicado: (2023)

Promotion of importin α–mediated nuclear import by the phosphorylation-dependent binding of cargo protein to 14-3-3
por: Faul, Christian, et al.
Publicado: (2005)

Structural characterization of human importin alpha 7 in its cargo-free form at 2.5 Å resolution
por: Tsimbalyuk, S., et al.
Publicado: (2022)

The structure of importin α and the nuclear localization peptide of ChREBP, and small compound inhibitors of ChREBP–importin α interactions
por: Jung, Hunmin, et al.
Publicado: (2020)

Transportin-SR, a Nuclear Import Receptor for SR Proteins
por: Kataoka, Naoyuki, et al.
Publicado: (1999)

Conservation of Importin α Function in Apicomplexans: Ivermectin and GW5074 Target Plasmodium falciparum Importin α and Inhibit Parasite Growth in Culture
por: Walunj, Sujata B., et al.
Publicado: (2022)

Importin/exportin-mediated nucleocytoplasmic shuttling of cucumber mosaic virus 2b protein is required for 2b’s efficient suppression of RNA silencing
por: Kim, Hangil, et al.
Publicado: (2022)

Transportin-2 plays a critical role in nucleocytoplasmic shuttling of oestrogen receptor-α
por: Moriyama, Tetsuji, et al.
Publicado: (2020)

An Importin Code in neuronal transport from synapse-to-nucleus?
por: Lever, Michael B., et al.
Publicado: (2015)

Data on dimer formation between importin α subtypes
por: Miyamoto, Yoichi, et al.
Publicado: (2016)

Importin-11 keeps PTEN safe from harm
por: Leslie, Nick R.
Publicado: (2017)

Importin-11 is Essential for Normal Embryonic Development in Mice
por: Lee, Ju-Young, et al.
Publicado: (2020)

Importin-13 genetic variation is associated with improved airway responsiveness in childhood asthma
por: Raby, Benjamin A, et al.
Publicado: (2009)

Importin-7 Mediates Nuclear Trafficking of DNA in Mammalian Cells
por: Dhanoya, Arjun, et al.
Publicado: (2013)

Importin α: functions as a nuclear transport factor and beyond
por: OKA, Masahiro, et al.
Publicado: (2018)

Importin binding mediates the intramolecular regulation of anillin during cytokinesis
por: Beaudet, Daniel, et al.
Publicado: (2020)

Differential Behaviours and Preferential Bindings of Influenza Nucleoproteins on Importins-α
por: Donchet, Amélie, et al.
Publicado: (2020)

Tick Importin-α Is Implicated in the Interactome and Regulome of the Cofactor Subolesin
por: Artigas-Jerónimo, Sara, et al.
Publicado: (2021)

Thioredoxin-related transmembrane protein 2 (TMX2) regulates the Ran protein gradient and importin-β-dependent nuclear cargo transport
por: Oguro, Ami, et al.
Publicado: (2019)

Interplay between HIV Entry and Transportin-SR2 Dependency
por: Thys, Wannes, et al.
Publicado: (2011)

Role of Transportin-SR2 in HIV-1 Nuclear Import
por: Tabasi, Maryam, et al.
Publicado: (2021)

Importin α5 negatively regulates importin β1-mediated nuclear import of Newcastle disease virus matrix protein and viral replication and pathogenicity in chicken fibroblasts
por: Duan, Zhiqiang, et al.
Publicado: (2018)

Nuclear import time and transport efficiency depend on importin β concentration
por: Yang, Weidong, et al.
Publicado: (2006)

Cannot write session to /tmp/vufind_sessions/sess_g2thoeigr5o79honfpdl291kbl