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Klotho inhibits neuronal senescence in human brain organoids

Aging is a major risk factor for many neurodegenerative diseases. Klotho (KL) is a glycosylated transmembrane protein that is expressed in the choroid plexus and neurons of the brain. KL exerts potent anti-aging effects on multiple cell types in the body but its role in human brain cells remains lar...

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Detalles Bibliográficos
Autores principales:	Shaker, Mohammed R., Aguado, Julio, Chaggar, Harman Kaur, Wolvetang, Ernst J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329278/ https://www.ncbi.nlm.nih.gov/pubmed/34341344 http://dx.doi.org/10.1038/s41514-021-00070-x

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