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Peroxisome-driven ether-linked phospholipids biosynthesis is essential for ferroptosis

It is well established that ferroptosis is primarily induced by peroxidation of long-chain poly-unsaturated fatty acid (PUFA) through nonenzymatic oxidation by free radicals or enzymatic stimulation of lipoxygenase. Although there is emerging evidence that long-chain saturated fatty acid (SFA) might...

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Detalles Bibliográficos
Autores principales: Cui, Weiwei, Liu, Dong, Gu, Wei, Chu, Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329287/
https://www.ncbi.nlm.nih.gov/pubmed/33731874
http://dx.doi.org/10.1038/s41418-021-00769-0