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Oncogene APOL1 promotes proliferation and inhibits apoptosis via activating NOTCH1 signaling pathway in pancreatic cancer

APOL1 encodes a secreted high-density lipoprotein, which has been considered as an aberrantly expressed gene in multiple cancers. Nevertheless, the role of APOL1 in the regulatory mechanisms of pancreatic cancer remains unknown and should be explored. We identified APOL1 was abnormally elevated in h...

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Detalles Bibliográficos
Autores principales: Lin, Jiewei, Xu, Zhiwei, Xie, Junjie, Deng, Xiaxing, Jiang, Lingxi, Chen, Hao, Peng, Chenghong, Li, Hongwei, Zhang, Jiaqiang, Shen, Baiyong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329288/
https://www.ncbi.nlm.nih.gov/pubmed/34341330
http://dx.doi.org/10.1038/s41419-021-03985-1

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