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Spotlight on the Compositional Quality of Probiotic Formulations Marketed Worldwide
On the worldwide market, a great number of probiotic formulations are available to consumers as drugs, dietary supplements, and functional foods. For exerting their beneficial effects on host health, these preparations should contain a sufficient amount of the indicated living microbes and be pathog...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329331/ https://www.ncbi.nlm.nih.gov/pubmed/34354690 http://dx.doi.org/10.3389/fmicb.2021.693973 |
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author | Mazzantini, Diletta Calvigioni, Marco Celandroni, Francesco Lupetti, Antonella Ghelardi, Emilia |
author_facet | Mazzantini, Diletta Calvigioni, Marco Celandroni, Francesco Lupetti, Antonella Ghelardi, Emilia |
author_sort | Mazzantini, Diletta |
collection | PubMed |
description | On the worldwide market, a great number of probiotic formulations are available to consumers as drugs, dietary supplements, and functional foods. For exerting their beneficial effects on host health, these preparations should contain a sufficient amount of the indicated living microbes and be pathogen-free to be safe. Therefore, the contained microbial species and their amount until product expiry are required to be accurately reported on the labels. While commercial formulations licensed as drugs are subjected to rigorous quality controls, less stringent regulations are generally applied to preparations categorized as dietary supplements and functional foods. Many reports indicated that the content of several probiotic formulations does not always correspond to the label claims in terms of microbial identification, number of living organisms, and purity, highlighting the requirement for more stringent quality controls by manufacturers. The main focus of this review is to provide an in-depth overview of the microbiological quality of probiotic formulations commercialized worldwide. Many incongruences in the compositional quality of some probiotic formulations available on the worldwide market were highlighted. Even if manufacturers carry at least some of the responsibility for these inconsistencies, studies that analyze probiotic products should be conducted following recommended and up-to-date methodologies. |
format | Online Article Text |
id | pubmed-8329331 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-83293312021-08-04 Spotlight on the Compositional Quality of Probiotic Formulations Marketed Worldwide Mazzantini, Diletta Calvigioni, Marco Celandroni, Francesco Lupetti, Antonella Ghelardi, Emilia Front Microbiol Microbiology On the worldwide market, a great number of probiotic formulations are available to consumers as drugs, dietary supplements, and functional foods. For exerting their beneficial effects on host health, these preparations should contain a sufficient amount of the indicated living microbes and be pathogen-free to be safe. Therefore, the contained microbial species and their amount until product expiry are required to be accurately reported on the labels. While commercial formulations licensed as drugs are subjected to rigorous quality controls, less stringent regulations are generally applied to preparations categorized as dietary supplements and functional foods. Many reports indicated that the content of several probiotic formulations does not always correspond to the label claims in terms of microbial identification, number of living organisms, and purity, highlighting the requirement for more stringent quality controls by manufacturers. The main focus of this review is to provide an in-depth overview of the microbiological quality of probiotic formulations commercialized worldwide. Many incongruences in the compositional quality of some probiotic formulations available on the worldwide market were highlighted. Even if manufacturers carry at least some of the responsibility for these inconsistencies, studies that analyze probiotic products should be conducted following recommended and up-to-date methodologies. Frontiers Media S.A. 2021-07-20 /pmc/articles/PMC8329331/ /pubmed/34354690 http://dx.doi.org/10.3389/fmicb.2021.693973 Text en Copyright © 2021 Mazzantini, Calvigioni, Celandroni, Lupetti and Ghelardi. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Microbiology Mazzantini, Diletta Calvigioni, Marco Celandroni, Francesco Lupetti, Antonella Ghelardi, Emilia Spotlight on the Compositional Quality of Probiotic Formulations Marketed Worldwide |
title | Spotlight on the Compositional Quality of Probiotic Formulations Marketed Worldwide |
title_full | Spotlight on the Compositional Quality of Probiotic Formulations Marketed Worldwide |
title_fullStr | Spotlight on the Compositional Quality of Probiotic Formulations Marketed Worldwide |
title_full_unstemmed | Spotlight on the Compositional Quality of Probiotic Formulations Marketed Worldwide |
title_short | Spotlight on the Compositional Quality of Probiotic Formulations Marketed Worldwide |
title_sort | spotlight on the compositional quality of probiotic formulations marketed worldwide |
topic | Microbiology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329331/ https://www.ncbi.nlm.nih.gov/pubmed/34354690 http://dx.doi.org/10.3389/fmicb.2021.693973 |
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