Treponema pallidum Disrupts VE-Cadherin Intercellular Junctions and Traverses Endothelial Barriers Using a Cholesterol-Dependent Mechanism

Treponema pallidum subspecies pallidum, the causative agent of syphilis, traverses the vascular endothelium to gain access to underlying tissue sites. Herein, we investigate the mechanisms associated with T. pallidum traversal of endothelial barriers. Immunofluorescence microscopy reveals that a sub...

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Detalles Bibliográficos
Autores principales: Lithgow, Karen V., Tsao, Emily, Schovanek, Ethan, Gomez, Alloysius, Swayne, Leigh Anne, Cameron, Caroline E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329343/
https://www.ncbi.nlm.nih.gov/pubmed/34354688
http://dx.doi.org/10.3389/fmicb.2021.691731

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