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PDIA6 promotes pancreatic cancer progression and immune escape through CSN5-mediated deubiquitination of β-catenin and PD-L1

Protein Disulfide Isomerase Family A Member 6 (PDIA6) is an endoplasmic reticulum protein that is capable of catalyzing protein folding and disulfide bond formation. Abnormally elevated expression of PDIA6 has been reported to predict poor outcomes in various cancers. Herein, gain-of- and loss-of-fu...

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Detalles Bibliográficos
Autores principales: Ma, Yihui, Xia, Peiyi, Wang, Zhengyang, Xu, Jingjing, Zhang, Lan, Jiang, Yanan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329431/
https://www.ncbi.nlm.nih.gov/pubmed/34325342
http://dx.doi.org/10.1016/j.neo.2021.07.004