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Physiologically Based Pharmacokinetic Modelling for Nicotine and Cotinine Clearance in Pregnant Women
Introduction: Physiologically based pharmacokinetic (PBPK) models for the absorption, disposition, metabolism and excretion (ADME) of nicotine and its major metabolite cotinine in pregnant women (p-PBPK) are rare. The aim of this short research report is to present a p-PBPK model and its simulations...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329445/ https://www.ncbi.nlm.nih.gov/pubmed/34354586 http://dx.doi.org/10.3389/fphar.2021.688597 |