Cargando…

Physiologically Based Pharmacokinetic Modelling for Nicotine and Cotinine Clearance in Pregnant Women

Introduction: Physiologically based pharmacokinetic (PBPK) models for the absorption, disposition, metabolism and excretion (ADME) of nicotine and its major metabolite cotinine in pregnant women (p-PBPK) are rare. The aim of this short research report is to present a p-PBPK model and its simulations...

Descripción completa

Detalles Bibliográficos
Autores principales:	Amice, Basile, Ho, Harvey, Zhang, En, Bullen, Chris
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329445/ https://www.ncbi.nlm.nih.gov/pubmed/34354586 http://dx.doi.org/10.3389/fphar.2021.688597

Ejemplares similares

P-glycoprotein efflux transporter: a key to pharmacokinetic modeling for methadone clearance in fetuses
por: Ho, Harvey, et al.
Publicado: (2023)

Saliva cotinine concentrations in pregnant women who smoke and use nicotine patches
por: Claire, Ravinder, et al.
Publicado: (2019)

Physiologically Based Pharmacokinetic Modeling in Pregnant Women Suggests Minor Decrease in Maternal Exposure to Olanzapine
por: Zheng, Liang, et al.
Publicado: (2022)

Cotinine Enhances Fear Extinction and Astrocyte Survival by Mechanisms Involving the Nicotinic Acetylcholine Receptors Signaling
por: Oliveros-Matus, Patricia, et al.
Publicado: (2020)

Comparison of Cotinine Levels in Pregnant Women While Smoking and When Using Nicotine Replacement Therapy
por: Bowker, Katharine A., et al.
Publicado: (2014)

Population Pharmacokinetics of Vancomycin in Pregnant Women
por: Goyal, Rahul K., et al.
Publicado: (2022)

Etravirine Pharmacokinetics in HIV-Infected Pregnant Women
por: Mulligan, Nikki, et al.
Publicado: (2016)

Human Blood Concentrations of Cotinine, a Biomonitoring Marker for Tobacco Smoke, Extrapolated from Nicotine Metabolism in Rats and Humans and Physiologically Based Pharmacokinetic Modeling
por: Yamazaki, Hiroshi, et al.
Publicado: (2010)

Unraveling bisphenol A pharmacokinetics using physiologically based pharmacokinetic modeling
por: Yang, Xiaoxia, et al.
Publicado: (2015)

MEGen: A Physiologically Based Pharmacokinetic Model Generator
por: Loizou, George, et al.
Publicado: (2011)

Population Pharmacokinetic Study of Cefathiamidine in Infants With Augmented Renal Clearance
por: Du, Bin, et al.
Publicado: (2021)

The Associations of Trans-3′-Hydroxy Cotinine, Cotinine, and the Nicotine Metabolite Ratio in Pediatric Patients with Tobacco Smoke Exposure
por: Mahabee-Gittens, E. Melinda, et al.
Publicado: (2023)

Population Pharmacokinetics of Praziquantel in Pregnant and Lactating Filipino Women Infected with Schistosoma japonicum
por: Bustinduy, Amaya L., et al.
Publicado: (2020)

Predictive performance and verification of physiologically based pharmacokinetic model of propylthiouracil
por: Shen, Chaozhuang, et al.
Publicado: (2022)

Cotinine: Beyond that Expected, More than a Biomarker of Tobacco Consumption
por: Moran, Valentina Echeverria
Publicado: (2012)

Estimation of Cutoff Values of Cotinine in Urine and Saliva for Pregnant Women in Poland
por: Stragierowicz, Joanna, et al.
Publicado: (2013)

Physiologically Based Pharmacokinetic Modeling to Understand the Absorption of Risperidone Orodispersible Film
por: Chen, Fang, et al.
Publicado: (2020)

First-in-human study to investigate the safety and pharmacokinetics of salvianolic acid A and pharmacokinetic simulation using a physiologically based pharmacokinetic model
por: Chen, Jinliang, et al.
Publicado: (2022)

Physiologic and pharmacokinetic changes in pregnancy
por: Costantine, Maged M.
Publicado: (2014)

Prediction of pyrotinib exposure based on physiologically-based pharmacokinetic model and endogenous biomarker
por: Zhang, Miao, et al.
Publicado: (2022)

A physiologically based pharmacokinetic model for V937 oncolytic virus in mice
por: Peribañez-Dominguez, Sara, et al.
Publicado: (2023)

Development of a population pharmacokinetic model of pyrazinamide to guide personalized therapy: impacts of geriatric and diabetes mellitus on clearance
por: Kim, Ryunha, et al.
Publicado: (2023)

Nicotine and cotinine in oral fluid: Passive exposure vs active smoking
por: Feng, Sheng, et al.
Publicado: (2018)

Cotinine: Pharmacologically Active Metabolite of Nicotine and Neural Mechanisms for Its Actions
por: Tan, Xiaoying, et al.
Publicado: (2021)

Pharmacokinetic Properties of Artemether, Dihydroartemisinin, Lumefantrine, and Quinine in Pregnant Women with Uncomplicated Plasmodium falciparum Malaria in Uganda
por: Tarning, Joel, et al.
Publicado: (2013)

Population Pharmacokinetics of Artemether, Dihydroartemisinin, and Lumefantrine in Rwandese Pregnant Women Treated for Uncomplicated Plasmodium falciparum Malaria
por: Lohy Das, Jesmin, et al.
Publicado: (2018)

Evaluation of vancomycin pharmacokinetics in patients with augmented renal clearances: A randomized clinical trial
por: Sahraei, Zahra, et al.
Publicado: (2022)

Use of physiological based pharmacokinetic modeling for cross-species prediction of pharmacokinetic and tissue distribution profiles of a novel niclosamide prodrug
por: Yang, Mengbi, et al.
Publicado: (2023)

The Future of Physiologically Based Pharmacokinetic Modeling to Predict Drug Exposure in Pregnant Women
por: Vinks, A A
Publicado: (2013)

A Physiologically Based Pharmacokinetic Model of Isoniazid and Its Application in Individualizing Tuberculosis Chemotherapy
por: Cordes, Henrik, et al.
Publicado: (2016)

Physiologically Based Pharmacokinetic Modeling of Monoclonal Antibodies in Pediatric Populations Using PK-Sim
por: Basu, Sumit, et al.
Publicado: (2020)

Physiologically based pharmacokinetic modeling of daptomycin dose optimization in pediatric patients with renal impairment
por: Ye, Lingling, et al.
Publicado: (2022)

Physiologically-based pharmacokinetic modelling and dosing evaluation of gentamicin in neonates using PhysPK
por: Zazo, Hinojal, et al.
Publicado: (2022)

Application of physiologically-based pharmacokinetic/pharmacodynamic models to evaluate the interaction between nifedipine and apatinib
por: Liu, Hongrui, et al.
Publicado: (2022)

Informing Pharmacokinetic Models With Physiological Data: Oral Population Modeling of L-Serine in Humans
por: Bosley, J. R., et al.
Publicado: (2021)

Artemether-Lumefantrine Pharmacokinetics and Clinical Response Are Minimally Altered in Pregnant Ugandan Women Treated for Uncomplicated Falciparum Malaria
por: Nyunt, Myaing M., et al.
Publicado: (2016)

A compatibility evaluation between the physiologically based pharmacokinetic (PBPK) model and the compartmental PK model using the lumping method with real cases
por: Ryu, Hyo-jeong, et al.
Publicado: (2022)

Application of Physiologically Based Pharmacokinetic Modeling to Evaluate the Drug–Drug and Drug–Disease Interactions of Apatinib
por: Liu, Hongrui, et al.
Publicado: (2021)

Potential drug-drug interaction of olverembatinib (HQP1351) using physiologically based pharmacokinetic models
por: Yu, Zhiheng, et al.
Publicado: (2022)

Pharmacokinetics and Disposition of Heparin-Binding Growth Factor Midkine Antisense Oligonucleotide Nanoliposomes in Experimental Animal Species and Prediction of Human Pharmacokinetics Using a Physiologically Based Pharmacokinetic Model
por: Bai, Haihong, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_2vhqvbk52n035om6rrfne29q5q