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Potential of Mitochondrial Genome Editing for Human Fertility Health

Mitochondrial DNA (mtDNA) encodes vital proteins and RNAs for the normal functioning of the mitochondria. Mutations in mtDNA leading to mitochondrial dysfunction are relevant to a large spectrum of diseases, including fertility disorders. Since mtDNA undergoes rather complex processes during gametog...

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Detalles Bibliográficos
Autores principales: Fu, Lin, Luo, Yu-Xin, Liu, Ying, Liu, Hui, Li, Hong-zhen, Yu, Yang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329452/
https://www.ncbi.nlm.nih.gov/pubmed/34354734
http://dx.doi.org/10.3389/fgene.2021.673951