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Successful pregnancy in morbidly obese lady with polycystic ovary syndrome after bariatric surgery: A case report

INTRODUCTION: Obesity has been proven to have adverse effects on fertility and is one of the predisposing factors for delay in pregnancy even with the use of assisted reproductive technique. There are many pathways in which obesity can affect fertility such as anovulation, poor implantation and low-...

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Autores principales: Pg Baharuddin, Dg Marshitah, Leik, Nang Kham Oo, Hayati, Firdaus, Mohd Daud, Mohd Nazri, See, Edwin, Sharif, Siti Zubaidah, Nik Lah, Nik Amin Sahid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329476/
https://www.ncbi.nlm.nih.gov/pubmed/34330067
http://dx.doi.org/10.1016/j.ijscr.2021.106235
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author Pg Baharuddin, Dg Marshitah
Leik, Nang Kham Oo
Hayati, Firdaus
Mohd Daud, Mohd Nazri
See, Edwin
Sharif, Siti Zubaidah
Nik Lah, Nik Amin Sahid
author_facet Pg Baharuddin, Dg Marshitah
Leik, Nang Kham Oo
Hayati, Firdaus
Mohd Daud, Mohd Nazri
See, Edwin
Sharif, Siti Zubaidah
Nik Lah, Nik Amin Sahid
author_sort Pg Baharuddin, Dg Marshitah
collection PubMed
description INTRODUCTION: Obesity has been proven to have adverse effects on fertility and is one of the predisposing factors for delay in pregnancy even with the use of assisted reproductive technique. There are many pathways in which obesity can affect fertility such as anovulation, poor implantation and low-quality oocyte. CASE PRESENTATION: We report a case of a 40-year-old lady with primary infertility for six years with underlying polycystic ovary syndrome (PCOS) and BMI 45.7 whom was successfully conceived twice following bariatric surgery procedure in which reduction of 70% of her BMI prior to bariatric surgery lead to her spontaneous conception without fertility intervention and successful live birth. CLINICAL DISCUSSION: Obese PCOS needs multidisciplinary approaches which include weight loss program such as dietary advice, exercise intervention as part of preliminary treatment prior to ovulation induction and counselling. CONCLUSION: Bariatric surgery has been a mainstay treatment in patients with morbid obesity and those with BMI more than 35 associated with obesity related problems such as joint pain, hypertension or diabetes mellitus. Bariatric surgery such as laparoscopic sleeve gastrectomy should be considered more often in contrast to lifestyle modification for morbidly obese lady with PCOS and infertility prior to the use of standard ovulation induction regime for treating infertility.
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spelling pubmed-83294762021-08-09 Successful pregnancy in morbidly obese lady with polycystic ovary syndrome after bariatric surgery: A case report Pg Baharuddin, Dg Marshitah Leik, Nang Kham Oo Hayati, Firdaus Mohd Daud, Mohd Nazri See, Edwin Sharif, Siti Zubaidah Nik Lah, Nik Amin Sahid Int J Surg Case Rep Case Report INTRODUCTION: Obesity has been proven to have adverse effects on fertility and is one of the predisposing factors for delay in pregnancy even with the use of assisted reproductive technique. There are many pathways in which obesity can affect fertility such as anovulation, poor implantation and low-quality oocyte. CASE PRESENTATION: We report a case of a 40-year-old lady with primary infertility for six years with underlying polycystic ovary syndrome (PCOS) and BMI 45.7 whom was successfully conceived twice following bariatric surgery procedure in which reduction of 70% of her BMI prior to bariatric surgery lead to her spontaneous conception without fertility intervention and successful live birth. CLINICAL DISCUSSION: Obese PCOS needs multidisciplinary approaches which include weight loss program such as dietary advice, exercise intervention as part of preliminary treatment prior to ovulation induction and counselling. CONCLUSION: Bariatric surgery has been a mainstay treatment in patients with morbid obesity and those with BMI more than 35 associated with obesity related problems such as joint pain, hypertension or diabetes mellitus. Bariatric surgery such as laparoscopic sleeve gastrectomy should be considered more often in contrast to lifestyle modification for morbidly obese lady with PCOS and infertility prior to the use of standard ovulation induction regime for treating infertility. Elsevier 2021-07-24 /pmc/articles/PMC8329476/ /pubmed/34330067 http://dx.doi.org/10.1016/j.ijscr.2021.106235 Text en © 2021 The Author(s) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Pg Baharuddin, Dg Marshitah
Leik, Nang Kham Oo
Hayati, Firdaus
Mohd Daud, Mohd Nazri
See, Edwin
Sharif, Siti Zubaidah
Nik Lah, Nik Amin Sahid
Successful pregnancy in morbidly obese lady with polycystic ovary syndrome after bariatric surgery: A case report
title Successful pregnancy in morbidly obese lady with polycystic ovary syndrome after bariatric surgery: A case report
title_full Successful pregnancy in morbidly obese lady with polycystic ovary syndrome after bariatric surgery: A case report
title_fullStr Successful pregnancy in morbidly obese lady with polycystic ovary syndrome after bariatric surgery: A case report
title_full_unstemmed Successful pregnancy in morbidly obese lady with polycystic ovary syndrome after bariatric surgery: A case report
title_short Successful pregnancy in morbidly obese lady with polycystic ovary syndrome after bariatric surgery: A case report
title_sort successful pregnancy in morbidly obese lady with polycystic ovary syndrome after bariatric surgery: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329476/
https://www.ncbi.nlm.nih.gov/pubmed/34330067
http://dx.doi.org/10.1016/j.ijscr.2021.106235
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