Determination of benchmark doses for linear furanocoumarin consumption associated with inhibition of cytochrome P450 1A2 isoenzyme activity in healthy human adults

Millions of individuals globally consume traditional herbal medicines (THMs), which contain abundant amounts of linear furanocoumarins. Linear furanocoumarins (i.e., 8-methoxypsoralen, 5-methoxypsoralen, and isopimpinellin) are inhibitors of cytochrome P450 (CYP) isoenzymes including 1A2, a major en...

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Detalles Bibliográficos
Autores principales: Alehaideb, Zeyad, Matou-Nasri, Sabine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Regular Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329502/
https://www.ncbi.nlm.nih.gov/pubmed/34377680
http://dx.doi.org/10.1016/j.toxrep.2021.07.013

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329502/
https://www.ncbi.nlm.nih.gov/pubmed/34377680
http://dx.doi.org/10.1016/j.toxrep.2021.07.013

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