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Dual Inhibition of PARP and the Intra-S/G2 Cell Cycle Checkpoints Results in Highly Effective Radiosensitization of HPV-Positive HNSCC Cells

In head and neck squamous cell carcinoma (HNSCC), tumors positive for human papillomavirus (HPV) represent a distinct biological entity with favorable prognosis. An enhanced radiation sensitivity of these tumors is evident in the clinic and on the cellular level when comparing HPV-positive and HPV-n...

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Detalles Bibliográficos
Autores principales:	Hintelmann, Katharina, Berenz, Thomas, Kriegs, Malte, Christiansen, Sabrina, Gatzemeier, Fruzsina, Struve, Nina, Petersen, Cordula, Betz, Christian, Rothkamm, Kai, Oetting, Agnes, Rieckmann, Thorsten
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Oncology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329549/ https://www.ncbi.nlm.nih.gov/pubmed/34354944 http://dx.doi.org/10.3389/fonc.2021.683688

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