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Structures of the Plasmodium falciparum heat-shock protein 70-x ATPase domain in complex with chemical fragments identify conserved and unique binding sites

Plasmodium falciparum invades erythrocytes and extensively modifies them in a manner that increases the virulence of this malaria parasite. A single heat-shock 70 kDa-type chaperone, PfHsp70-x, is among the parasite proteins exported to the host cell. PfHsp70-x assists in the formation of a key prot...

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Detalles Bibliográficos
Autores principales:	Mohamad, Nada, O’Donoghue, Ailsa, Kantsadi, Anastassia L., Vakonakis, Ioannis
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Union of Crystallography 2021
Materias:	Research Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329712/ https://www.ncbi.nlm.nih.gov/pubmed/34341192 http://dx.doi.org/10.1107/S2053230X21007378

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