Cargando…

Structures of full-length VanR from Streptomyces coelicolor in both the inactive and activated states

Vancomycin has historically been used as a last-resort treatment for serious bacterial infections. However, vancomycin resistance has become widespread in certain pathogens, presenting a serious threat to public health. Resistance to vancomycin is conferred by a suite of resistance genes, the expres...

Descripción completa

Detalles Bibliográficos
Autores principales: Maciunas, Lina J., Porter, Nadia, Lee, Paula J., Gupta, Kushol, Loll, Patrick J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329863/
https://www.ncbi.nlm.nih.gov/pubmed/34342276
http://dx.doi.org/10.1107/S2059798321006288