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Immune Gene Rearrangements: Unique Signatures for Tracing Physiological Lymphocytes and Leukemic Cells

The tremendous diversity of the human immune repertoire, fundamental for the defense against highly heterogeneous pathogens, is based on the ingenious mechanism of immune gene rearrangements. Rearranged immune genes encoding the immunoglobulins and T-cell receptors and thus determining each lymphocy...

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Detalles Bibliográficos
Autores principales: Kotrova, Michaela, Darzentas, Nikos, Pott, Christiane, Baldus, Claudia D., Brüggemann, Monika
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329920/
https://www.ncbi.nlm.nih.gov/pubmed/34198966
http://dx.doi.org/10.3390/genes12070979