Native and oxidised lipoproteins negatively regulate the serum amyloid A‐induced NLRP3 inflammasome activation in human macrophages

OBJECTIVES: The NLRP3 inflammasome plays a key role in arterial wall inflammation. In this study, we elucidated the role of serum lipoproteins in the regulation of NLRP3 inflammasome activation by serum amyloid A (SAA) and other inflammasome activators. METHODS: The effect of lipoproteins on the NLR...

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Detalles Bibliográficos
Autores principales: Nurmi, Katariina, Niemi, Katri, Kareinen, Ilona, Silventoinen, Kristiina, Lorey, Martina B, Chen, Yan, Kouri, Vesa‐Petteri, Parantainen, Jukka, Juutilainen, Timo, Öörni, Katariina, Kovanen, Petri T, Nordström, Dan, Matikainen, Sampsa, Eklund, Kari K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329955/
https://www.ncbi.nlm.nih.gov/pubmed/34377468
http://dx.doi.org/10.1002/cti2.1323

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