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Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk

Idiopathic pulmonary fibrosis (IPF) is characterized by devastating and progressive lung parenchymal fibrosis, resulting in poor patient prognosis. An aberrant recapitulation of developmental lung gene expression, including genes for transforming growth factor (TGF)‐β and WNT, has been widely implic...

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Detalles Bibliográficos
Autores principales: Kadota, Tsukasa, Fujita, Yu, Araya, Jun, Watanabe, Naoaki, Fujimoto, Shota, Kawamoto, Hironori, Minagawa, Shunsuke, Hara, Hiromichi, Ohtsuka, Takashi, Yamamoto, Yusuke, Kuwano, Kazuyoshi, Ochiya, Takahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329991/
https://www.ncbi.nlm.nih.gov/pubmed/34377373
http://dx.doi.org/10.1002/jev2.12124