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Human bronchial epithelial cell‐derived extracellular vesicle therapy for pulmonary fibrosis via inhibition of TGF‐β‐WNT crosstalk
Idiopathic pulmonary fibrosis (IPF) is characterized by devastating and progressive lung parenchymal fibrosis, resulting in poor patient prognosis. An aberrant recapitulation of developmental lung gene expression, including genes for transforming growth factor (TGF)‐β and WNT, has been widely implic...
Autores principales: | Kadota, Tsukasa, Fujita, Yu, Araya, Jun, Watanabe, Naoaki, Fujimoto, Shota, Kawamoto, Hironori, Minagawa, Shunsuke, Hara, Hiromichi, Ohtsuka, Takashi, Yamamoto, Yusuke, Kuwano, Kazuyoshi, Ochiya, Takahiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8329991/ https://www.ncbi.nlm.nih.gov/pubmed/34377373 http://dx.doi.org/10.1002/jev2.12124 |
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