Thrombomodulin is associated with increased mortality and organ failure in mechanically ventilated children with acute respiratory failure: biomarker analysis from a multicenter randomized controlled trial

BACKGROUND: Acute respiratory failure (ARF) can progress to acute respiratory distress syndrome and death. Biomarkers may allow for risk stratification and prognostic enrichment in ARF. Thrombomodulin (TM) is a transmembrane antithrombotic mediator expressed in endothelial cells. It is cleaved into...

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Detalles Bibliográficos
Autores principales: Monteiro, Ana Carolina Costa, Flori, Heidi, Dahmer, Mary K., Sim, Myung Shin, Quasney, Michael W., Curley, Martha A. Q., Matthay, Michael A., Sapru, Anil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330123/
https://www.ncbi.nlm.nih.gov/pubmed/34344416
http://dx.doi.org/10.1186/s13054-021-03626-1

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