Clonal Hematopoiesis and COVID-19 Severity in Cancer Patients

Background: Advanced age, medical co-morbidities and a pro-inflammatory immunologic profile are associated with severe COVID-19. Acquired somatic mutations in hematopoietic stem cells (clonal hematopoiesis or CH) are common in elderly individuals. Previous studies have shown CH is associated with al...

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Detalles Bibliográficos
Autores principales: Bolton, Kelly L., Foote, Michael, Jee, Justin, Safonov, Anton, Ptashkin, Ryan, Devlin, Sean, Gedvilaite, Erika, Gao, Teng, Papaemmanuil, Elli, Pessin, Melissa S., Kamboj, Mini, Vijai, Joseph, Offit, Kenneth, Awadalla, Phillip, Nataranjan, Pradeep, Berger, Michael F., Norton, Larry, Levine, Ross L., Zehir, Ahmet
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Hematology 2020
Materias:
503.Clonal Hematopoiesis: Aging and Inflammation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330325/
http://dx.doi.org/10.1182/blood-2020-143041

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