A Review of Hepatorenal Syndrome

The development of acute kidney injury (AKI) is one of the most frequent complications in patients with cirrhosis. AKI due to volume depletion is the most common etiology and hepatorenal syndrome (HRS) is the second most common cause of AKI in these patients. HRS is the extreme form of kidney injury...

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Autores principales: Subedi, Abinash, Suresh Kumar, Vishnu Charan, Sharma Subedi, Aakritee, Sapkota, Bishnu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Internal Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330394/
https://www.ncbi.nlm.nih.gov/pubmed/34367745
http://dx.doi.org/10.7759/cureus.16084
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author Subedi, Abinash
Suresh Kumar, Vishnu Charan
Sharma Subedi, Aakritee
Sapkota, Bishnu
author_facet Subedi, Abinash
Suresh Kumar, Vishnu Charan
Sharma Subedi, Aakritee
Sapkota, Bishnu
author_sort Subedi, Abinash
collection PubMed
description The development of acute kidney injury (AKI) is one of the most frequent complications in patients with cirrhosis. AKI due to volume depletion is the most common etiology and hepatorenal syndrome (HRS) is the second most common cause of AKI in these patients. HRS is the extreme form of kidney injury in patients with cirrhosis, which is caused due to a reduction in renal blood flow unresponsive to volume expansion. The literature involving HRS is rapidly evolving and newer tests and updated definitions have been proposed which allows timely identification and treatment. Here, we will discuss the definition, pathophysiology, prevention, diagnosis, and treatment of HRS.
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spelling pubmed-83303942021-08-06 A Review of Hepatorenal Syndrome Subedi, Abinash Suresh Kumar, Vishnu Charan Sharma Subedi, Aakritee Sapkota, Bishnu Cureus Internal Medicine The development of acute kidney injury (AKI) is one of the most frequent complications in patients with cirrhosis. AKI due to volume depletion is the most common etiology and hepatorenal syndrome (HRS) is the second most common cause of AKI in these patients. HRS is the extreme form of kidney injury in patients with cirrhosis, which is caused due to a reduction in renal blood flow unresponsive to volume expansion. The literature involving HRS is rapidly evolving and newer tests and updated definitions have been proposed which allows timely identification and treatment. Here, we will discuss the definition, pathophysiology, prevention, diagnosis, and treatment of HRS. Cureus 2021-07-01 /pmc/articles/PMC8330394/ /pubmed/34367745 http://dx.doi.org/10.7759/cureus.16084 Text en Copyright © 2021, Subedi et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Internal Medicine
Subedi, Abinash
Suresh Kumar, Vishnu Charan
Sharma Subedi, Aakritee
Sapkota, Bishnu
A Review of Hepatorenal Syndrome
title A Review of Hepatorenal Syndrome
title_full A Review of Hepatorenal Syndrome
title_fullStr A Review of Hepatorenal Syndrome
title_full_unstemmed A Review of Hepatorenal Syndrome
title_short A Review of Hepatorenal Syndrome
title_sort review of hepatorenal syndrome
topic Internal Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330394/
https://www.ncbi.nlm.nih.gov/pubmed/34367745
http://dx.doi.org/10.7759/cureus.16084
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