Cargando…
Transfer hydrogenations catalyzed by streptavidin-hosted secondary amine organocatalysts
Here, the streptavidin–biotin technology was applied to enable organocatalytic transfer hydrogenation. By introducing a biotin-tethered pyrrolidine (1) to the tetrameric streptavidin (T-Sav), the resulting hybrid catalyst was able to mediate hydride transfer from dihydro-benzylnicotinamide (BNAH) to...
Autores principales: | Santi, Nicolò, Morrill, Louis C., Świderek, Katarzyna, Moliner, Vicent, Luk, Louis Y. P. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330412/ https://www.ncbi.nlm.nih.gov/pubmed/33496282 http://dx.doi.org/10.1039/d0cc08142f |
Ejemplares similares
-
The role of streptavidin and its variants in catalysis by biotinylated secondary amines
por: Nödling, Alexander R., et al.
Publicado: (2021) -
Streptavidin-Hosted Organocatalytic Aldol Addition
por: Santi, Nicolò, et al.
Publicado: (2020) -
Reactivity and Selectivity of Iminium Organocatalysis Improved by a Protein Host
por: Nödling, Alexander R., et al.
Publicado: (2018) -
Combined Theoretical and Experimental Study to Unravel the Differences in Promiscuous
Amidase Activity of Two Nonhomologous Enzymes
por: Galmés, Miquel À., et al.
Publicado: (2021) -
FLP‐Catalyzed Transfer Hydrogenation of Silyl Enol Ethers
por: Khan, Imtiaz, et al.
Publicado: (2018)