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Transfer hydrogenations catalyzed by streptavidin-hosted secondary amine organocatalysts

Here, the streptavidin–biotin technology was applied to enable organocatalytic transfer hydrogenation. By introducing a biotin-tethered pyrrolidine (1) to the tetrameric streptavidin (T-Sav), the resulting hybrid catalyst was able to mediate hydride transfer from dihydro-benzylnicotinamide (BNAH) to...

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Detalles Bibliográficos
Autores principales: Santi, Nicolò, Morrill, Louis C., Świderek, Katarzyna, Moliner, Vicent, Luk, Louis Y. P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330412/
https://www.ncbi.nlm.nih.gov/pubmed/33496282
http://dx.doi.org/10.1039/d0cc08142f

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