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The small molecule kobusone can stimulate islet β-cell replication in vivo
OBJECTIVE: To investigate the ability of kobusone to reduce high glucose levels and promote β-cell proliferation. METHODS: Four-week-old female db/db mice were assigned to the kobusone (25 mg/kg body weight, intraperitoneally twice a day) or control group (same volume of PBS). Glucose levels and bod...
Autores principales: | Choi, Jin woo, Joo, Jin-deok, In, Jang hyeok, Kim, Daewoo, Kim, Yongshin, Choi, Seung Tae, Kim, Jung Han, Jung, Hong Soo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
SAGE Publications
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330483/ https://www.ncbi.nlm.nih.gov/pubmed/34320857 http://dx.doi.org/10.1177/03000605211032849 |
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