FGFR/RACK1 interacts with MDM2, promotes P53 degradation, and inhibits cell senescence in lung squamous cell carcinoma

OBJECTIVE: FGFR is considered an important driver gene of lung squamous cell carcinoma (LSCC). Thus, identification of the biological events downstream of FGFR is important for the treatment of this malignancy. Our previous study has shown that the FGFR/RACK1 complex interacts with PKM2 and conseque...

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Detalles Bibliográficos
Autores principales: Chen, Tao, Wang, Fei, Wei, Shupei, Nie, Yingjie, Zheng, Xiaotao, Deng, Yu, Zhu, Xubin, Deng, Yuezhen, Zhong, Nanshan, Zhou, Chengzhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330524/
https://www.ncbi.nlm.nih.gov/pubmed/33710818
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0389

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330524/
https://www.ncbi.nlm.nih.gov/pubmed/33710818
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0389

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