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FGFR/RACK1 interacts with MDM2, promotes P53 degradation, and inhibits cell senescence in lung squamous cell carcinoma
OBJECTIVE: FGFR is considered an important driver gene of lung squamous cell carcinoma (LSCC). Thus, identification of the biological events downstream of FGFR is important for the treatment of this malignancy. Our previous study has shown that the FGFR/RACK1 complex interacts with PKM2 and conseque...
Autores principales: | Chen, Tao, Wang, Fei, Wei, Shupei, Nie, Yingjie, Zheng, Xiaotao, Deng, Yu, Zhu, Xubin, Deng, Yuezhen, Zhong, Nanshan, Zhou, Chengzhi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Compuscript
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330524/ https://www.ncbi.nlm.nih.gov/pubmed/33710818 http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0389 |
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