Heat shock protein 90 promotes RNA helicase DDX5 accumulation and exacerbates hepatocellular carcinoma by inhibiting autophagy

OBJECTIVE: Hepatocellular carcinoma (HCC), the main type of liver cancer, has a high morbidity and mortality, and a poor prognosis. RNA helicase DDX5, which acts as a transcriptional co-regulator, is overexpressed in most malignant tumors and promotes cancer cell growth. Heat shock protein 90 (HSP90...

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Detalles Bibliográficos
Autores principales: Zhang, Ting, Yang, Xinrui, Xu, Wanping, Wang, Jing, Wu, Dawei, Hong, Zhixian, Yuan, Shengxian, Zeng, Zhen, Jia, Xiaodong, Lu, Shanshan, Safadi, Rifaat, Han, Sen, Yang, Zhihong, Neckers, Leonard M., Liangpunsakul, Suthat, Zhou, Weiping, Lu, Yinying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Compuscript 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330532/
https://www.ncbi.nlm.nih.gov/pubmed/33764710
http://dx.doi.org/10.20892/j.issn.2095-3941.2020.0262

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