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CD8(+) T Cell Exhaustion in Cancer

A paradigm shift in the understanding of the exhausted CD8(+) T cell (T(ex)) lineage is underway. Originally thought to be a uniform population that progressively loses effector function in response to persistent antigen, single-cell analysis has now revealed that CD8(+) T(ex) is composed of multipl...

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Detalles Bibliográficos
Autores principales: Dolina, Joseph S., Van Braeckel-Budimir, Natalija, Thomas, Graham D., Salek-Ardakani, Shahram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330547/
https://www.ncbi.nlm.nih.gov/pubmed/34354714
http://dx.doi.org/10.3389/fimmu.2021.715234