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Protective lipid-lowering variants in healthy older individuals without coronary heart disease

OBJECTIVE: Genetic variants that disrupt the function of the PCSK9 (proprotein convertase subtilisin kexin type 9) and APOB (apolipoprotein B)genes result in lower serum low-density lipoprotein cholesterol (LDL-C) levels and subsequently confer protection against coronary heart disease (CHD). The ob...

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Detalles Bibliográficos
Autores principales:	Lacaze, Paul, Riaz, Moeen, Sebra, Robert, Hooper, Amanda J, Pang, Jing, Tiller, Jane, Polekhina, Galina, Tonkin, Andrew, Reid, Chris, Zoungas, Sophia, Murray, Anne M, Nicholls, Stephen, Watts, Gerald, Schadt, Eric, McNeil, John J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Special Populations
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330577/ https://www.ncbi.nlm.nih.gov/pubmed/34341098 http://dx.doi.org/10.1136/openhrt-2021-001710

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