HPV-16 E6/E7 DNA tattoo vaccination using genetically optimized vaccines elicit clinical and immunological responses in patients with usual vulvar intraepithelial neoplasia (uVIN): a phase I/II clinical trial

BACKGROUND: Usual vulvar intraepithelial neoplasia (uVIN) is a premalignancy caused by persistent infection with high-risk types of human papillomavirus (HPV), mainly type 16. Even though different treatment modalities are available (eg, surgical excision, laser evaporation or topical application of...

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Detalles Bibliográficos
Autores principales: Bakker, Noor Alida Maria, Rotman, Jossie, van Beurden, Marc, Zijlmans, Henry J MAA, van Ruiten, Maartje, Samuels, Sanne, Nuijen, Bastiaan, Beijnen, Jos, De Visser, Karin, Haanen, John, Schumacher, Ton, de Gruijl, Tanja D, Jordanova, Ekaterina S, Kenter, Gemma G, van den Berg, Joost H, van Trommel, Nienke E
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Clinical/Translational Cancer Immunotherapy
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330588/
https://www.ncbi.nlm.nih.gov/pubmed/34341131
http://dx.doi.org/10.1136/jitc-2021-002547

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