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Deceased Donor Renal Transplantation: A Single Center Experience
INTRODUCTION: Deceased donor kidney transplant are still not common across India. This study was done to assess various measures taken at a single center level to increase organ donation rate and to analyse the outcomes of transplants performed from these donors. METHODS: All deceased donor renal tr...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer - Medknow
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330647/ https://www.ncbi.nlm.nih.gov/pubmed/34376939 http://dx.doi.org/10.4103/ijn.IJN_66_20 |
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author | Kapoor, Kunal Kumar, Sandeep Sharma, Ashish Kenwar, Deepesh Benjamin Singh, Sarbpreet Shiva, S. P. Kohli, Harbir Singh Kaur, Rajinder |
author_facet | Kapoor, Kunal Kumar, Sandeep Sharma, Ashish Kenwar, Deepesh Benjamin Singh, Sarbpreet Shiva, S. P. Kohli, Harbir Singh Kaur, Rajinder |
author_sort | Kapoor, Kunal |
collection | PubMed |
description | INTRODUCTION: Deceased donor kidney transplant are still not common across India. This study was done to assess various measures taken at a single center level to increase organ donation rate and to analyse the outcomes of transplants performed from these donors. METHODS: All deceased donor renal transplants performed from November 2011 to February 2017 were analysed for patient and death censored graft survival, rate of delayed graft function, rate of rejection and mortality. Kaplan Meir analysis for Survival Curves was used. RESULTS: Organ donation rate at our center improved from one donation every alternate year in 2004 to a peak of 44 donations in 2017. Patient survival was 93.42%, 89.44%, 85.53%, and death censored graft survival was 94.07%, 88.21%, and 82.86% at 1, 2 and 3 years respectively. Mean duration of hemodialysis pre transplantation was 34.6 ± 27.43 months. CONCLUSIONS: This study has shown that steps taken at a single center level alone can also significantly improve organ donation rates. Employment of dedicated professionals including transplant surgeons and coordinators, developing a protocol-based approach for referral, and early counseling in triage along with regular audits can help to establish deceased donor program with acceptable outcomes elsewhere in the country. |
format | Online Article Text |
id | pubmed-8330647 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Wolters Kluwer - Medknow |
record_format | MEDLINE/PubMed |
spelling | pubmed-83306472021-08-09 Deceased Donor Renal Transplantation: A Single Center Experience Kapoor, Kunal Kumar, Sandeep Sharma, Ashish Kenwar, Deepesh Benjamin Singh, Sarbpreet Shiva, S. P. Kohli, Harbir Singh Kaur, Rajinder Indian J Nephrol Original Article INTRODUCTION: Deceased donor kidney transplant are still not common across India. This study was done to assess various measures taken at a single center level to increase organ donation rate and to analyse the outcomes of transplants performed from these donors. METHODS: All deceased donor renal transplants performed from November 2011 to February 2017 were analysed for patient and death censored graft survival, rate of delayed graft function, rate of rejection and mortality. Kaplan Meir analysis for Survival Curves was used. RESULTS: Organ donation rate at our center improved from one donation every alternate year in 2004 to a peak of 44 donations in 2017. Patient survival was 93.42%, 89.44%, 85.53%, and death censored graft survival was 94.07%, 88.21%, and 82.86% at 1, 2 and 3 years respectively. Mean duration of hemodialysis pre transplantation was 34.6 ± 27.43 months. CONCLUSIONS: This study has shown that steps taken at a single center level alone can also significantly improve organ donation rates. Employment of dedicated professionals including transplant surgeons and coordinators, developing a protocol-based approach for referral, and early counseling in triage along with regular audits can help to establish deceased donor program with acceptable outcomes elsewhere in the country. Wolters Kluwer - Medknow 2021 2021-04-10 /pmc/articles/PMC8330647/ /pubmed/34376939 http://dx.doi.org/10.4103/ijn.IJN_66_20 Text en Copyright: © 2021 Indian Journal of Nephrology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms. |
spellingShingle | Original Article Kapoor, Kunal Kumar, Sandeep Sharma, Ashish Kenwar, Deepesh Benjamin Singh, Sarbpreet Shiva, S. P. Kohli, Harbir Singh Kaur, Rajinder Deceased Donor Renal Transplantation: A Single Center Experience |
title | Deceased Donor Renal Transplantation: A Single Center Experience |
title_full | Deceased Donor Renal Transplantation: A Single Center Experience |
title_fullStr | Deceased Donor Renal Transplantation: A Single Center Experience |
title_full_unstemmed | Deceased Donor Renal Transplantation: A Single Center Experience |
title_short | Deceased Donor Renal Transplantation: A Single Center Experience |
title_sort | deceased donor renal transplantation: a single center experience |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330647/ https://www.ncbi.nlm.nih.gov/pubmed/34376939 http://dx.doi.org/10.4103/ijn.IJN_66_20 |
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