Cargando…

Deceased Donor Renal Transplantation: A Single Center Experience

INTRODUCTION: Deceased donor kidney transplant are still not common across India. This study was done to assess various measures taken at a single center level to increase organ donation rate and to analyse the outcomes of transplants performed from these donors. METHODS: All deceased donor renal tr...

Descripción completa

Detalles Bibliográficos
Autores principales: Kapoor, Kunal, Kumar, Sandeep, Sharma, Ashish, Kenwar, Deepesh Benjamin, Singh, Sarbpreet, Shiva, S. P., Kohli, Harbir Singh, Kaur, Rajinder
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330647/
https://www.ncbi.nlm.nih.gov/pubmed/34376939
http://dx.doi.org/10.4103/ijn.IJN_66_20
_version_ 1783732761812533248
author Kapoor, Kunal
Kumar, Sandeep
Sharma, Ashish
Kenwar, Deepesh Benjamin
Singh, Sarbpreet
Shiva, S. P.
Kohli, Harbir Singh
Kaur, Rajinder
author_facet Kapoor, Kunal
Kumar, Sandeep
Sharma, Ashish
Kenwar, Deepesh Benjamin
Singh, Sarbpreet
Shiva, S. P.
Kohli, Harbir Singh
Kaur, Rajinder
author_sort Kapoor, Kunal
collection PubMed
description INTRODUCTION: Deceased donor kidney transplant are still not common across India. This study was done to assess various measures taken at a single center level to increase organ donation rate and to analyse the outcomes of transplants performed from these donors. METHODS: All deceased donor renal transplants performed from November 2011 to February 2017 were analysed for patient and death censored graft survival, rate of delayed graft function, rate of rejection and mortality. Kaplan Meir analysis for Survival Curves was used. RESULTS: Organ donation rate at our center improved from one donation every alternate year in 2004 to a peak of 44 donations in 2017. Patient survival was 93.42%, 89.44%, 85.53%, and death censored graft survival was 94.07%, 88.21%, and 82.86% at 1, 2 and 3 years respectively. Mean duration of hemodialysis pre transplantation was 34.6 ± 27.43 months. CONCLUSIONS: This study has shown that steps taken at a single center level alone can also significantly improve organ donation rates. Employment of dedicated professionals including transplant surgeons and coordinators, developing a protocol-based approach for referral, and early counseling in triage along with regular audits can help to establish deceased donor program with acceptable outcomes elsewhere in the country.
format Online
Article
Text
id pubmed-8330647
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-83306472021-08-09 Deceased Donor Renal Transplantation: A Single Center Experience Kapoor, Kunal Kumar, Sandeep Sharma, Ashish Kenwar, Deepesh Benjamin Singh, Sarbpreet Shiva, S. P. Kohli, Harbir Singh Kaur, Rajinder Indian J Nephrol Original Article INTRODUCTION: Deceased donor kidney transplant are still not common across India. This study was done to assess various measures taken at a single center level to increase organ donation rate and to analyse the outcomes of transplants performed from these donors. METHODS: All deceased donor renal transplants performed from November 2011 to February 2017 were analysed for patient and death censored graft survival, rate of delayed graft function, rate of rejection and mortality. Kaplan Meir analysis for Survival Curves was used. RESULTS: Organ donation rate at our center improved from one donation every alternate year in 2004 to a peak of 44 donations in 2017. Patient survival was 93.42%, 89.44%, 85.53%, and death censored graft survival was 94.07%, 88.21%, and 82.86% at 1, 2 and 3 years respectively. Mean duration of hemodialysis pre transplantation was 34.6 ± 27.43 months. CONCLUSIONS: This study has shown that steps taken at a single center level alone can also significantly improve organ donation rates. Employment of dedicated professionals including transplant surgeons and coordinators, developing a protocol-based approach for referral, and early counseling in triage along with regular audits can help to establish deceased donor program with acceptable outcomes elsewhere in the country. Wolters Kluwer - Medknow 2021 2021-04-10 /pmc/articles/PMC8330647/ /pubmed/34376939 http://dx.doi.org/10.4103/ijn.IJN_66_20 Text en Copyright: © 2021 Indian Journal of Nephrology https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kapoor, Kunal
Kumar, Sandeep
Sharma, Ashish
Kenwar, Deepesh Benjamin
Singh, Sarbpreet
Shiva, S. P.
Kohli, Harbir Singh
Kaur, Rajinder
Deceased Donor Renal Transplantation: A Single Center Experience
title Deceased Donor Renal Transplantation: A Single Center Experience
title_full Deceased Donor Renal Transplantation: A Single Center Experience
title_fullStr Deceased Donor Renal Transplantation: A Single Center Experience
title_full_unstemmed Deceased Donor Renal Transplantation: A Single Center Experience
title_short Deceased Donor Renal Transplantation: A Single Center Experience
title_sort deceased donor renal transplantation: a single center experience
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330647/
https://www.ncbi.nlm.nih.gov/pubmed/34376939
http://dx.doi.org/10.4103/ijn.IJN_66_20
work_keys_str_mv AT kapoorkunal deceaseddonorrenaltransplantationasinglecenterexperience
AT kumarsandeep deceaseddonorrenaltransplantationasinglecenterexperience
AT sharmaashish deceaseddonorrenaltransplantationasinglecenterexperience
AT kenwardeepeshbenjamin deceaseddonorrenaltransplantationasinglecenterexperience
AT singhsarbpreet deceaseddonorrenaltransplantationasinglecenterexperience
AT shivasp deceaseddonorrenaltransplantationasinglecenterexperience
AT kohliharbirsingh deceaseddonorrenaltransplantationasinglecenterexperience
AT kaurrajinder deceaseddonorrenaltransplantationasinglecenterexperience