Discovery of new 3-methylquinoxalines as potential anti-cancer agents and apoptosis inducers targeting VEGFR-2: design, synthesis, and in silico studies

There is an urgent need to design new anticancer agents that can prevent cancer cell proliferation even with minimal side effects. Accordingly, two new series of 3-methylquinoxalin-2(1H)-one and 3-methylquinoxaline-2-thiol derivatives were designed to act as VEGFR-2 inhibitors. The designed derivati...

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Detalles Bibliográficos
Autores principales: Alanazi, Mohammed M., Alaa, Elwan, Alsaif, Nawaf A., Obaidullah, Ahmad J., Alkahtani, Hamad M., Al-Mehizia, Abdulrahman A., Alsubaie, Sultan M., Taghour, Mohammed S., Eissa, Ibrahim H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330740/
https://www.ncbi.nlm.nih.gov/pubmed/34325596
http://dx.doi.org/10.1080/14756366.2021.1945591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330740/
https://www.ncbi.nlm.nih.gov/pubmed/34325596
http://dx.doi.org/10.1080/14756366.2021.1945591

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