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Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint
Significance: Fourier ptychography (FP) is a computational imaging approach that achieves high-resolution reconstruction. Inspired by neural networks, many deep-learning-based methods are proposed to solve FP problems. However, the performance of FP still suffers from optical aberration, which needs...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Society of Photo-Optical Instrumentation Engineers
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330837/ https://www.ncbi.nlm.nih.gov/pubmed/33768741 http://dx.doi.org/10.1117/1.JBO.26.3.036502 |
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author | Zhang, Yongbing Liu, Yangzhe Jiang, Shaowei Dixit, Krishna Song, Pengming Zhang, Xinfeng Ji, Xiangyang Li, Xiu |
author_facet | Zhang, Yongbing Liu, Yangzhe Jiang, Shaowei Dixit, Krishna Song, Pengming Zhang, Xinfeng Ji, Xiangyang Li, Xiu |
author_sort | Zhang, Yongbing |
collection | PubMed |
description | Significance: Fourier ptychography (FP) is a computational imaging approach that achieves high-resolution reconstruction. Inspired by neural networks, many deep-learning-based methods are proposed to solve FP problems. However, the performance of FP still suffers from optical aberration, which needs to be considered. Aim: We present a neural network model for FP reconstructions that can make proper estimation toward aberration and achieve artifact-free reconstruction. Approach: Inspired by the iterative reconstruction of FP, we design a neural network model that mimics the forward imaging process of FP via TensorFlow. The sample and aberration are considered as learnable weights and optimized through back-propagation. Especially, we employ the Zernike terms instead of aberration to decrease the optimization freedom of pupil recovery and perform a high-accuracy estimation. Owing to the auto-differentiation capabilities of the neural network, we additionally utilize total variation regularization to improve the visual quality. Results: We validate the performance of the reported method via both simulation and experiment. Our method exhibits higher robustness against sophisticated optical aberrations and achieves better image quality by reducing artifacts. Conclusions: The forward neural network model can jointly recover the high-resolution sample and optical aberration in iterative FP reconstruction. We hope our method that can provide a neural-network perspective to solve iterative-based coherent or incoherent imaging problems. |
format | Online Article Text |
id | pubmed-8330837 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Society of Photo-Optical Instrumentation Engineers |
record_format | MEDLINE/PubMed |
spelling | pubmed-83308372021-08-06 Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint Zhang, Yongbing Liu, Yangzhe Jiang, Shaowei Dixit, Krishna Song, Pengming Zhang, Xinfeng Ji, Xiangyang Li, Xiu J Biomed Opt Microscopy Significance: Fourier ptychography (FP) is a computational imaging approach that achieves high-resolution reconstruction. Inspired by neural networks, many deep-learning-based methods are proposed to solve FP problems. However, the performance of FP still suffers from optical aberration, which needs to be considered. Aim: We present a neural network model for FP reconstructions that can make proper estimation toward aberration and achieve artifact-free reconstruction. Approach: Inspired by the iterative reconstruction of FP, we design a neural network model that mimics the forward imaging process of FP via TensorFlow. The sample and aberration are considered as learnable weights and optimized through back-propagation. Especially, we employ the Zernike terms instead of aberration to decrease the optimization freedom of pupil recovery and perform a high-accuracy estimation. Owing to the auto-differentiation capabilities of the neural network, we additionally utilize total variation regularization to improve the visual quality. Results: We validate the performance of the reported method via both simulation and experiment. Our method exhibits higher robustness against sophisticated optical aberrations and achieves better image quality by reducing artifacts. Conclusions: The forward neural network model can jointly recover the high-resolution sample and optical aberration in iterative FP reconstruction. We hope our method that can provide a neural-network perspective to solve iterative-based coherent or incoherent imaging problems. Society of Photo-Optical Instrumentation Engineers 2021-03-25 2021-03 /pmc/articles/PMC8330837/ /pubmed/33768741 http://dx.doi.org/10.1117/1.JBO.26.3.036502 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI. |
spellingShingle | Microscopy Zhang, Yongbing Liu, Yangzhe Jiang, Shaowei Dixit, Krishna Song, Pengming Zhang, Xinfeng Ji, Xiangyang Li, Xiu Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint |
title | Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint |
title_full | Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint |
title_fullStr | Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint |
title_full_unstemmed | Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint |
title_short | Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint |
title_sort | neural network model assisted fourier ptychography with zernike aberration recovery and total variation constraint |
topic | Microscopy |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330837/ https://www.ncbi.nlm.nih.gov/pubmed/33768741 http://dx.doi.org/10.1117/1.JBO.26.3.036502 |
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