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Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint

Significance: Fourier ptychography (FP) is a computational imaging approach that achieves high-resolution reconstruction. Inspired by neural networks, many deep-learning-based methods are proposed to solve FP problems. However, the performance of FP still suffers from optical aberration, which needs...

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Autores principales: Zhang, Yongbing, Liu, Yangzhe, Jiang, Shaowei, Dixit, Krishna, Song, Pengming, Zhang, Xinfeng, Ji, Xiangyang, Li, Xiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society of Photo-Optical Instrumentation Engineers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330837/
https://www.ncbi.nlm.nih.gov/pubmed/33768741
http://dx.doi.org/10.1117/1.JBO.26.3.036502
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author Zhang, Yongbing
Liu, Yangzhe
Jiang, Shaowei
Dixit, Krishna
Song, Pengming
Zhang, Xinfeng
Ji, Xiangyang
Li, Xiu
author_facet Zhang, Yongbing
Liu, Yangzhe
Jiang, Shaowei
Dixit, Krishna
Song, Pengming
Zhang, Xinfeng
Ji, Xiangyang
Li, Xiu
author_sort Zhang, Yongbing
collection PubMed
description Significance: Fourier ptychography (FP) is a computational imaging approach that achieves high-resolution reconstruction. Inspired by neural networks, many deep-learning-based methods are proposed to solve FP problems. However, the performance of FP still suffers from optical aberration, which needs to be considered. Aim: We present a neural network model for FP reconstructions that can make proper estimation toward aberration and achieve artifact-free reconstruction. Approach: Inspired by the iterative reconstruction of FP, we design a neural network model that mimics the forward imaging process of FP via TensorFlow. The sample and aberration are considered as learnable weights and optimized through back-propagation. Especially, we employ the Zernike terms instead of aberration to decrease the optimization freedom of pupil recovery and perform a high-accuracy estimation. Owing to the auto-differentiation capabilities of the neural network, we additionally utilize total variation regularization to improve the visual quality. Results: We validate the performance of the reported method via both simulation and experiment. Our method exhibits higher robustness against sophisticated optical aberrations and achieves better image quality by reducing artifacts. Conclusions: The forward neural network model can jointly recover the high-resolution sample and optical aberration in iterative FP reconstruction. We hope our method that can provide a neural-network perspective to solve iterative-based coherent or incoherent imaging problems.
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spelling pubmed-83308372021-08-06 Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint Zhang, Yongbing Liu, Yangzhe Jiang, Shaowei Dixit, Krishna Song, Pengming Zhang, Xinfeng Ji, Xiangyang Li, Xiu J Biomed Opt Microscopy Significance: Fourier ptychography (FP) is a computational imaging approach that achieves high-resolution reconstruction. Inspired by neural networks, many deep-learning-based methods are proposed to solve FP problems. However, the performance of FP still suffers from optical aberration, which needs to be considered. Aim: We present a neural network model for FP reconstructions that can make proper estimation toward aberration and achieve artifact-free reconstruction. Approach: Inspired by the iterative reconstruction of FP, we design a neural network model that mimics the forward imaging process of FP via TensorFlow. The sample and aberration are considered as learnable weights and optimized through back-propagation. Especially, we employ the Zernike terms instead of aberration to decrease the optimization freedom of pupil recovery and perform a high-accuracy estimation. Owing to the auto-differentiation capabilities of the neural network, we additionally utilize total variation regularization to improve the visual quality. Results: We validate the performance of the reported method via both simulation and experiment. Our method exhibits higher robustness against sophisticated optical aberrations and achieves better image quality by reducing artifacts. Conclusions: The forward neural network model can jointly recover the high-resolution sample and optical aberration in iterative FP reconstruction. We hope our method that can provide a neural-network perspective to solve iterative-based coherent or incoherent imaging problems. Society of Photo-Optical Instrumentation Engineers 2021-03-25 2021-03 /pmc/articles/PMC8330837/ /pubmed/33768741 http://dx.doi.org/10.1117/1.JBO.26.3.036502 Text en © 2021 The Authors https://creativecommons.org/licenses/by/4.0/Published by SPIE under a Creative Commons Attribution 4.0 Unported License. Distribution or reproduction of this work in whole or in part requires full attribution of the original publication, including its DOI.
spellingShingle Microscopy
Zhang, Yongbing
Liu, Yangzhe
Jiang, Shaowei
Dixit, Krishna
Song, Pengming
Zhang, Xinfeng
Ji, Xiangyang
Li, Xiu
Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint
title Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint
title_full Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint
title_fullStr Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint
title_full_unstemmed Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint
title_short Neural network model assisted Fourier ptychography with Zernike aberration recovery and total variation constraint
title_sort neural network model assisted fourier ptychography with zernike aberration recovery and total variation constraint
topic Microscopy
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8330837/
https://www.ncbi.nlm.nih.gov/pubmed/33768741
http://dx.doi.org/10.1117/1.JBO.26.3.036502
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