Preoperative imaging of glioblastoma patients using hyperpolarized (13)C pyruvate: Potential role in clinical decision making

BACKGROUND: Glioblastoma remains incurable despite treatment with surgery, radiation therapy, and cytotoxic chemotherapy, prompting the search for a metabolic pathway unique to glioblastoma cells.(13)C MR spectroscopic imaging with hyperpolarized pyruvate can demonstrate alterations in pyruvate meta...

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Detalles Bibliográficos
Autores principales: Chen, Jun, Patel, Toral R, Pinho, Marco C, Choi, Changho, Harrison, Crystal E, Baxter, Jeannie D, Derner, Kelley, Pena, Salvador, Liticker, Jeff, Raza, Jaffar, Hall, Ronald G, Reed, Galen D, Cai, Chunyu, Hatanpaa, Kimmo J, Bankson, James A, Bachoo, Robert M, Malloy, Craig R, Mickey, Bruce E, Park, Jae Mo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Basic and Translational Investigations
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331053/
https://www.ncbi.nlm.nih.gov/pubmed/34355174
http://dx.doi.org/10.1093/noajnl/vdab092

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