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Ocrelizumab for the Treatment of Multiple Sclerosis: Safety, Efficacy, and Pharmacology

The success of selective B-cells depleting therapies, as the anti-CD20 antibodies, in patients with multiple sclerosis (MS) has confirmed that B-cells are critical in the immune pathogenesis of the disease. Ocrelizumab, a humanized monoclonal antibody that selectively targets CD20+ B-cells, profound...

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Detalles Bibliográficos
Autores principales:	Mancinelli, Chiara Rosa, Rossi, Nicola De, Capra, Ruggero
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove 2021
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331077/ https://www.ncbi.nlm.nih.gov/pubmed/34354358 http://dx.doi.org/10.2147/TCRM.S282390

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