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Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules

We describe MIP-1 and MIP-2, novel paralogous C. elegans germ granule components that interact with the intrinsically disordered MEG-3 protein. These proteins promote P granule condensation, form granules independently of MEG-3 in the postembryonic germ line, and balance each other in regulating P g...

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Detalles Bibliográficos
Autores principales: Cipriani, Patricia Giselle, Bay, Olivia, Zinno, John, Gutwein, Michelle, Gan, Hin Hark, Mayya, Vinay K, Chung, George, Chen, Jia-Xuan, Fahs, Hala, Guan, Yu, Duchaine, Thomas F, Selbach, Matthias, Piano, Fabio, Gunsalus, Kristin C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331183/
https://www.ncbi.nlm.nih.gov/pubmed/34223818
http://dx.doi.org/10.7554/eLife.60833

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