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Novel LOTUS-domain proteins are organizational hubs that recruit C. elegans Vasa to germ granules
We describe MIP-1 and MIP-2, novel paralogous C. elegans germ granule components that interact with the intrinsically disordered MEG-3 protein. These proteins promote P granule condensation, form granules independently of MEG-3 in the postembryonic germ line, and balance each other in regulating P g...
Autores principales: | Cipriani, Patricia Giselle, Bay, Olivia, Zinno, John, Gutwein, Michelle, Gan, Hin Hark, Mayya, Vinay K, Chung, George, Chen, Jia-Xuan, Fahs, Hala, Guan, Yu, Duchaine, Thomas F, Selbach, Matthias, Piano, Fabio, Gunsalus, Kristin C |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331183/ https://www.ncbi.nlm.nih.gov/pubmed/34223818 http://dx.doi.org/10.7554/eLife.60833 |
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