Transcriptional Regulator Induced Phenotype screen reveals drug potentiators in Mycobacterium tuberculosis

Transposon-based strategies provide a powerful and unbiased way to study bacterial stress response(1–8), but these approaches cannot fully capture the complexities of network-based behavior. Here, we present a network-based genetic screening approach: the Transcriptional Regulator Induced Phenotype...

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Detalles Bibliográficos
Autores principales: Ma, Shuyi, Morrison, Robert, Hobbs, Samuel J., Soni, Vijay, Farrow-Johnson, Jessica, Frando, Andrew, Fleck, Neil, Grundner, Christoph, Rhee, Kyu Y., Rustad, Tige R., Sherman, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331221/
https://www.ncbi.nlm.nih.gov/pubmed/33199862
http://dx.doi.org/10.1038/s41564-020-00810-x

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