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Mepolizumab decreased the levels of serum galectin-10 and eosinophil cationic protein in asthma
BACKGROUND: Mepolizumab, a humanized antibody targeting interleukin-5, decreases the number of blood eosinophils and the frequency of exacerbation of severe asthma. Galectin-10 is a protein within the cytoplasm of eosinophils and constitutes Charcot-Leyden crystals, which promotes key features of as...
Autores principales: | Kobayashi, Konomi, Nagase, Hiroyuki, Sugimoto, Naoya, Yamamoto, Shiho, Tanaka, Akihiko, Fukunaga, Koichi, Atsuta, Ryo, Tagaya, Etsuko, Hojo, Masayuki, Gon, Yasuhiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Asia Pacific Association of Allergy, Asthma and Clinical Immunology
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331256/ https://www.ncbi.nlm.nih.gov/pubmed/34386407 http://dx.doi.org/10.5415/apallergy.2021.11.e31 |
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