L-type amino acid transporter 1 inhibitor suppresses murine Th2 cell-mediated bronchial hyperresponsiveness independently of eosinophil accumulation

BACKGROUND: The activation of Th2 cells that play a pivotal role in the development of allergic eosinophilic inflammation is regulated by an L-type amino acid transporter (LAT) 1. However, the contribution of LAT1 to the pathogenesis of Th2 cell-mediated airway inflammation has not been investigated...

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Detalles Bibliográficos
Autores principales: Ito, Daiki, Miura, Kento, Saeki, Mayumi, Yamasaki, Norimasa, Ogata, Sawako, Koyama, Teidai, Hiroi, Takachika, Mori, Akio, Endou, Hitoshi, Hayashi, Keitaro, Kaminuma, Osamu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Asia Pacific Association of Allergy, Asthma and Clinical Immunology 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331261/
https://www.ncbi.nlm.nih.gov/pubmed/34386409
http://dx.doi.org/10.5415/apallergy.2021.11.e33

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