Cargando…

GC-MS Based Metabolomics Reveals the Synergistic Mechanism of Gardeniae Fructus-Forsythiae Fructus Herb Pair in Lipopolysaccharide-Induced Acute Lung Injury Mouse Model

Compatibility remains among the crucial and significant characteristics of traditional Chinese medicines. The Gardeniae Fructus (FG)-Forsythiae Fructus (FF) herb pair, an epitome of formulations for heat-clearing and detoxification, is extensively used to treat bacterial pneumonia in clinical settin...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wu, Wenhui, Lin, Huiqing, Yin, Ailing, Shen, Cunsi, Zhou, Hongliang, Wang, Majie, Yu, Heming, Wang, Haidan, Zhang, Zhihao, Zhou, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8331283/ https://www.ncbi.nlm.nih.gov/pubmed/34354760 http://dx.doi.org/10.1155/2021/8064557

Ejemplares similares

Chemistry and pharmacology of the herb pair Flos Lonicerae japonicae-Forsythiae fructus
por: Guo, Yi-ping, et al.
Publicado: (2015)

Improvement of Intestinal Absorption of Forsythoside A and Chlorogenic Acid by Different Carboxymethyl Chitosan and Chito-oligosaccharide, Application to Flos Lonicerae - Fructus Forsythiae Herb Couple Preparations
por: Zhou, Wei, et al.
Publicado: (2013)

The combination of Lonicerae Japonicae Flos and Forsythiae Fructus herb-pair alleviated inflammation in liver fibrosis
por: Zhang, Jing-Bei, et al.
Publicado: (2022)

Therapeutic Potential and Effective Components of the Chinese Herb Gardeniae Fructus in the Treatment of Senile Disease
por: Lv, Shichao, et al.
Publicado: (2018)

Study on the Rationality for Antiviral Activity of Flos Lonicerae Japonicae-Fructus Forsythiae Herb Couple Preparations Improved by Chito-Oligosaccharide via Integral Pharmacokinetics
por: Zhou, Wei, et al.
Publicado: (2017)

Better detoxifying effect of ripe forsythiae fructus over green forsythiae fructus and the potential mechanisms involving bile acids metabolism and gut microbiota
por: Wang, Tao, et al.
Publicado: (2022)

Pharmacokinetic Evaluation of Clozapine in Concomitant Use of Radix Rehmanniae, Fructus Schisandrae, Radix Bupleuri, or Fructus Gardeniae in Rats
por: Tian, Dan-Dan, et al.
Publicado: (2016)

Isoflavones' effects on pharmacokinetic profiles of main iridoids from Gardeniae Fructus in rats
por: Chang, Ruirui, et al.
Publicado: (2020)

Study on the Main Components Interaction from Flos Lonicerae and Fructus Forsythiae and Their Dissolution In Vitro and Intestinal Absorption in Rats
por: Zhou, Wei, et al.
Publicado: (2014)

Multi-omics analysis reveals the molecular basis of flavonoid accumulation in fructus of Gardenia (Gardenia jasminoides Ellis)
por: Chen, Jianrong, et al.
Publicado: (2023)

Distribution Patterns for Bioactive Constituents in Pericarp, Stalk and Seed of Forsythiae Fructus
por: Wei, Lifang, et al.
Publicado: (2020)

Effects of Long-Term Administration of Gardeniae Fructus on Intra-Abdominal Organs of Rats
por: Takei, Hisato, et al.
Publicado: (2020)

Mitochondrial-Respiration-Improving Effects of Three Different Gardeniae Fructus Preparations and Their Components
por: Wang, Yun, et al.
Publicado: (2021)

Forsythiae Fructus: A Review on its Phytochemistry, Quality Control, Pharmacology and Pharmacokinetics
por: Dong, Zhanglu, et al.
Publicado: (2017)

Investigation of the hemostatic mechanism of Gardeniae fructus Praeparatus based on pharmacological evaluation and network pharmacology
por: Zheng, Yinghao, et al.
Publicado: (2022)

A Study of the Anti-Cancer Effects of the Hexane Fraction of the Methanol Extract of Forsythiae Fructus
por: Lee, Se-Eun, et al.
Publicado: (2017)

Discovery and Current Status of Evaluation System of Bioavailability and Related Pharmaceutical Technologies for Traditional Chinese Medicines—Flos Lonicerae Japonicae—Fructus Forsythiae Herb Couples as an Example
por: Zhou, Wei, et al.
Publicado: (2015)

Anti-depressant effects of oil from fructus gardeniae via PKA-CREB-BDNF signaling
por: Ruan, Jie, et al.
Publicado: (2019)

Study on Mechanism of Iridoid Glycosides Derivatives from Fructus Gardeniae in Jiangxi Province by Network Pharmacology
por: Liu, Fangzhou, et al.
Publicado: (2020)

Screening of the Hepatotoxic Components in Fructus Gardeniae and Their Effects on Rat Liver BRL-3A Cells
por: Li, Chunnan, et al.
Publicado: (2019)

Effects of Multi-Strain Probiotics Combined with Gardeniae fructus on Intestinal Microbiota, Metabolites, and Morphology in Broilers
por: Chang, Chi Huan, et al.
Publicado: (2019)

Determining the Stir-Frying Degree of Gardeniae Fructus Praeparatus Based on Deep Learning and Transfer Learning
por: Zhang, Yuzhen, et al.
Publicado: (2022)

A STUDY OF THE ANTI-INFLAMMATORY EFFECTS OF THE ETHYL ACETATE FRACTION OF THE METHANOL EXTRACT OF FORSYTHIAE FRUCTUS
por: Lee, Se-Eun, et al.
Publicado: (2016)

Application of Scutellariae radix, Gardeniae fructus, and Probiotics to Prevent Salmonella enterica Serovar Choleraesuis Infection in Swine
por: Chang, Chiung-Hung, et al.
Publicado: (2013)

Treatment Mechanism of Gardeniae Fructus and Its Carbonized Product Against Ethanol-Induced Gastric Lesions in Rats
por: Zhang, Xue, et al.
Publicado: (2019)

Antibacterial Activity of Fructus forsythia Essential Oil and the Application of EO-Loaded Nanoparticles to Food-Borne Pathogens
por: Guo, Na, et al.
Publicado: (2016)

Comparative Evaluation of Forsythiae Fructus From Different Harvest Seasons and Regions by HPLC/NIR Analysis and Anti-inflammatory and Antioxidant Assays
por: Qu, Qian, et al.
Publicado: (2021)

Pharmacological systemic analysis of gardenia fructus against non-alcoholic fatty liver disease and validation of animal models
por: Lee, Kang Pa, et al.
Publicado: (2022)

Development of the Volatile Fingerprint of Qu Aurantii Fructus by HS-GC-IMS
por: Fang, Cuifen, et al.
Publicado: (2022)

Accelerated Solvent Extraction of Antioxidant Compounds from Gardeniae Fructus and Its Acetylcholinesterase Inhibitory and PC12 Cell Protective Activities
por: Fan, Yiling, et al.
Publicado: (2021)

Synergistic Protective Effect of Fermented Schizandrae Fructus Pomace and Hoveniae Semen cum Fructus Extracts Mixture in the Ethanol-Induced Hepatotoxicity
por: Jegal, Kyung-Hwan, et al.
Publicado: (2023)

Exploring Anti-Nonalcoholic Fatty Liver Disease Mechanism of Gardeniae Fructus by Network Pharmacology, Molecular Docking, and Experiment Validation
por: Tang, Zhongyan, et al.
Publicado: (2022)

Fructus gardeniae ameliorates anxiety-like behaviors induced by sleep deprivation via regulating hippocampal metabolomics and gut microbiota
por: Liu, Dong, et al.
Publicado: (2023)

Identification and Comparison of Constituents of Aurantii Fructus and Aurantii Fructus Immaturus by UFLC-DAD-Triple TOF-MS/MS
por: Bai, Yang, et al.
Publicado: (2018)

Forsythiasides-Rich Extract From Forsythiae Fructus Inhibits Mast Cell Degranulation by Enhancing Mitochondrial Ca(2+) Uptake
por: Qi, Ruijuan, et al.
Publicado: (2021)

Understanding the molecular mechanism of Ginkgo Folium-Forsythiae Fructus for cerebral atherosclerosis treatment using network pharmacology and molecular docking
por: Zhang, Jinfei, et al.
Publicado: (2023)

The Potential Antipyretic Mechanism of Gardeniae Fructus and Its Heat-Processed Products With Plasma Metabolomics Using Rats With Yeast-Induced Fever
por: Zhang, Xue, et al.
Publicado: (2019)

Geniposide, a Principal Component of Gardeniae Fructus, Protects Skin from Diesel Exhaust Particulate Matter-Induced Oxidative Damage
por: Nguyen, Ly Thi Huong, et al.
Publicado: (2021)

A Novel Method for Quality Evaluation of Gardeniae fructus Praeparatus during Heat Processing Based on Sensory Characteristics and Chemical Compositions
por: Zheng, Yinghao, et al.
Publicado: (2022)

A Mixture of Fermented Schizandrae Fructus Pomace and Hoveniae Semen cum Fructus Extracts Synergistically Protects against Oxidative Stress-Mediated Liver Injury
por: Kim, Jang-Soo, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_hla6m1m09ghe56eh6lhj4fa8mi