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Effects of Renal Impairment on the Pharmacokinetics of the Dual GIP and GLP-1 Receptor Agonist Tirzepatide

BACKGROUND AND AIMS: The pharmacokinetics (PK) and single-dose tolerability of tirzepatide, a dual glucose-dependent insulinotropic polypeptide and glucagon-like peptide-1 receptor agonist being developed for once-weekly treatment of type 2 diabetes (T2D), weight management, and nonalcoholic steatoh...

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Detalles Bibliográficos
Autores principales: Urva, Shweta, Quinlan, Tonya, Landry, John, Martin, Jennifer, Loghin, Corina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332596/
https://www.ncbi.nlm.nih.gov/pubmed/33778934
http://dx.doi.org/10.1007/s40262-021-01012-2

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