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Knock-in of the duck retinoic acid-inducible gene I (RIG-I) into the Mx gene in DF-1 cells enables both stable and immune response-dependent RIG-I expression

Waterfowls, such as ducks, are natural hosts of avian influenza virus (AIV) and can genetically limit the pathogenicity. On the other hand, some AIV strains cause severe pathogenicity in chickens. It is suggested that differences in the pathogenicity of AIV infection between waterfowls and chickens...

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Detalles Bibliográficos
Autores principales: Ichikawa, Kennosuke, Motoe, Yuzuha, Ezaki, Ryo, Matsuzaki, Mei, Horiuchi, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332658/
https://www.ncbi.nlm.nih.gov/pubmed/34381879
http://dx.doi.org/10.1016/j.bbrep.2021.101084

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