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Exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests

OBJECTIVE: To investigate the validity of field walking tests to identify exercise-induced hypoxemia and to compare cardiorespiratory responses and perceived effort between laboratory-based and field-based exercise tests in subjects with bronchiectasis. METHODS: This was a cross-sectional study invo...

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Autores principales: de Oliveira, Cristiane Helga Yamane, José, Anderson, de Camargo, Anderson Alves, Feltrim, Maria Ignez Zanetti, Athanazio, Rodrigo Abensur, Rached, Samia Zahi, Stelmalch, Rafael, Corso, Simone Dal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Pneumologia e Tisiologia 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332849/
https://www.ncbi.nlm.nih.gov/pubmed/33656157
http://dx.doi.org/10.36416/1806-3756/e20200134
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author de Oliveira, Cristiane Helga Yamane
José, Anderson
de Camargo, Anderson Alves
Feltrim, Maria Ignez Zanetti
Athanazio, Rodrigo Abensur
Rached, Samia Zahi
Stelmalch, Rafael
Corso, Simone Dal
author_facet de Oliveira, Cristiane Helga Yamane
José, Anderson
de Camargo, Anderson Alves
Feltrim, Maria Ignez Zanetti
Athanazio, Rodrigo Abensur
Rached, Samia Zahi
Stelmalch, Rafael
Corso, Simone Dal
author_sort de Oliveira, Cristiane Helga Yamane
collection PubMed
description OBJECTIVE: To investigate the validity of field walking tests to identify exercise-induced hypoxemia and to compare cardiorespiratory responses and perceived effort between laboratory-based and field-based exercise tests in subjects with bronchiectasis. METHODS: This was a cross-sectional study involving 72 non-oxygen-dependent participants (28 men; mean age = 48.3 ± 14.5 years; and mean FEV(1) = 54.1 ± 23.4% of the predicted value). The participants underwent cardiopulmonary exercise testing (CPET) on a treadmill and constant work-rate exercise testing (CWRET) on the same day (1 h apart). In another visit, they underwent incremental shuttle walk testing (ISWT) and endurance shuttle walk testing (ESWT; 1 h apart). Desaturation was defined as a reduction in SpO(2) ≥ 4% from rest to peak exercise. RESULTS: CPET results were compared with ISWT results, as were CWRET results with ESWT results. There was no difference in the magnitude of desaturation between CPET and ISWT (−7.7 ± 6.3% vs. −6.6 ± 5.6%; p = 0.10) and between CWRET and ESWT (−6.8 ± 5.8% vs. −7.2 ± 6.3%; p = 0.50). The incremental tests showed an agreement in the magnitude of desaturation in the desaturation and no desaturation groups (42 and 14 participants, respectively; p < 0.01), as did the endurance tests (39 and 16 participants; p < 0.01). The magnitude of desaturation was similar among the participants who did or did not reach at least 85% of the maximum predicted HR. CONCLUSIONS: Field exercise tests showed good precision to detect desaturation. Field tests might be an alternative to laboratory tests when the clinical question is to investigate exercise-induced desaturation in subjects with bronchiectasis.
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spelling pubmed-83328492021-08-08 Exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests de Oliveira, Cristiane Helga Yamane José, Anderson de Camargo, Anderson Alves Feltrim, Maria Ignez Zanetti Athanazio, Rodrigo Abensur Rached, Samia Zahi Stelmalch, Rafael Corso, Simone Dal J Bras Pneumol Original Article OBJECTIVE: To investigate the validity of field walking tests to identify exercise-induced hypoxemia and to compare cardiorespiratory responses and perceived effort between laboratory-based and field-based exercise tests in subjects with bronchiectasis. METHODS: This was a cross-sectional study involving 72 non-oxygen-dependent participants (28 men; mean age = 48.3 ± 14.5 years; and mean FEV(1) = 54.1 ± 23.4% of the predicted value). The participants underwent cardiopulmonary exercise testing (CPET) on a treadmill and constant work-rate exercise testing (CWRET) on the same day (1 h apart). In another visit, they underwent incremental shuttle walk testing (ISWT) and endurance shuttle walk testing (ESWT; 1 h apart). Desaturation was defined as a reduction in SpO(2) ≥ 4% from rest to peak exercise. RESULTS: CPET results were compared with ISWT results, as were CWRET results with ESWT results. There was no difference in the magnitude of desaturation between CPET and ISWT (−7.7 ± 6.3% vs. −6.6 ± 5.6%; p = 0.10) and between CWRET and ESWT (−6.8 ± 5.8% vs. −7.2 ± 6.3%; p = 0.50). The incremental tests showed an agreement in the magnitude of desaturation in the desaturation and no desaturation groups (42 and 14 participants, respectively; p < 0.01), as did the endurance tests (39 and 16 participants; p < 0.01). The magnitude of desaturation was similar among the participants who did or did not reach at least 85% of the maximum predicted HR. CONCLUSIONS: Field exercise tests showed good precision to detect desaturation. Field tests might be an alternative to laboratory tests when the clinical question is to investigate exercise-induced desaturation in subjects with bronchiectasis. Sociedade Brasileira de Pneumologia e Tisiologia 2021 /pmc/articles/PMC8332849/ /pubmed/33656157 http://dx.doi.org/10.36416/1806-3756/e20200134 Text en © 2021 Sociedade Brasileira de Pneumologia e Tisiologia https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Original Article
de Oliveira, Cristiane Helga Yamane
José, Anderson
de Camargo, Anderson Alves
Feltrim, Maria Ignez Zanetti
Athanazio, Rodrigo Abensur
Rached, Samia Zahi
Stelmalch, Rafael
Corso, Simone Dal
Exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests
title Exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests
title_full Exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests
title_fullStr Exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests
title_full_unstemmed Exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests
title_short Exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests
title_sort exercise-induced desaturation in subjects with non-cystic fibrosis bronchiectasis: laboratory-based tests versus field-based exercise tests
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8332849/
https://www.ncbi.nlm.nih.gov/pubmed/33656157
http://dx.doi.org/10.36416/1806-3756/e20200134
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