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3D-printed titanium implant combined with interleukin 4 regulates ordered macrophage polarization to promote bone regeneration and angiogenesis

AIMS: The use of 3D-printed titanium implant (DT) can effectively guide bone regeneration. DT triggers a continuous host immune reaction, including macrophage type 1 polarization, that resists osseointegration. Interleukin 4 (IL4) is a specific cytokine modulating osteogenic capability that switches...

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Detalles Bibliográficos
Autores principales:	Zhao, Da-Wang, Ren, Bing, Wang, Hong-Wei, Zhang, Xiao, Yu, Ming-Zhi, Cheng, Lei, Sang, Yuan-Hua, Cao, Shuai-Shuai, Thieringer, Florian M., Zhang, Dong, Wan, Yi, Liu, Chao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Editorial Society of Bone & Joint Surgery 2021
Materias:	Biomaterials
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333031/ https://www.ncbi.nlm.nih.gov/pubmed/34259564 http://dx.doi.org/10.1302/2046-3758.107.BJR-2020-0334.R4

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