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PARP-1 inhibition attenuates the inflammatory response in the cartilage of a rat model of osteoarthritis

AIMS: Poly (ADP-ribose) polymerase (PARP) inhibitor has been reported to attenuate inflammatory response in rat models of inflammation. This study was designed to investigate the effect of PARP signalling in osteoarthritis (OA) cartilage inflammatory response in an OA rat model. METHODS: The OA mode...

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Detalles Bibliográficos
Autores principales:	Liu, Zili, Wang, Honglin, Wang, Shaoqian, Gao, Jie, Niu, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The British Editorial Society of Bone & Joint Surgery 2021
Materias:	Arthritis
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333032/ https://www.ncbi.nlm.nih.gov/pubmed/34254815 http://dx.doi.org/10.1302/2046-3758.107.BJR-2020-0200.R2

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