Cargando…

Transcriptomic landscape of blood platelets in healthy donors

Blood platelet RNA-sequencing is increasingly used among the scientific community. Aberrant platelet transcriptome is common in cancer or cardiovascular disease, but reference data on platelet RNA content in healthy individuals are scarce and merit complex investigation. We sought to explore the dyn...

Descripción completa

Detalles Bibliográficos
Autores principales:	Supernat, Anna, Popęda, Marta, Pastuszak, Krzysztof, Best, Myron G., Grešner, Peter, Veld, Sjors In ’t, Siek, Bartłomiej, Bednarz-Knoll, Natalia, Rondina, Matthew T., Stokowy, Tomasz, Wurdinger, Thomas, Jassem, Jacek, Żaczek, Anna J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8333095/ https://www.ncbi.nlm.nih.gov/pubmed/34344933 http://dx.doi.org/10.1038/s41598-021-94003-z

Ejemplares similares

imPlatelet classifier: image‐converted RNA biomarker profiles enable blood‐based cancer diagnostics
por: Pastuszak, Krzysztof, et al.
Publicado: (2021)

Diagnostic Accuracy of Liquid Biopsy in Endometrial Cancer
por: Łukasiewicz, Marta, et al.
Publicado: (2021)

Platelet-Based Liquid Biopsies through the Lens of Machine Learning
por: Cygert, Sebastian, et al.
Publicado: (2023)

Reduced expression of innate immunity-related genes in lymph node metastases of luminal breast cancer patients
por: Popeda, Marta, et al.
Publicado: (2021)

NF-kappa B Signaling-Related Signatures Are Connected with the Mesenchymal Phenotype of Circulating Tumor Cells in Non-Metastatic Breast Cancer
por: Popeda, Marta, et al.
Publicado: (2019)

Alpha-smooth muscle actin-positive cancer-associated fibroblasts secreting osteopontin promote growth of luminal breast cancer
por: Muchlińska, Anna, et al.
Publicado: (2022)

Blood platelet RNA enables the detection of multiple sclerosis
por: Sol, Nik, et al.
Publicado: (2020)

Discrimination Between Pre‐ and Postcapillary Pulmonary Hypertension Using Platelet RNA
por: Arkani, Mohammad, et al.
Publicado: (2023)

Platelet RNA enables accurate detection of ovarian cancer: an intercontinental, biomarker identification study
por: Gao, Yue, et al.
Publicado: (2022)

Blood platelets as an RNA biomarker platform for neuro-oncological diseases
por: Post, Edward, et al.
Publicado: (2022)

RNA-Sequencing of Tumor-Educated Platelets, a Novel Biomarker for Blood-Based Sarcoma Diagnostics
por: Heinhuis, Kimberley M., et al.
Publicado: (2020)

Detection and Characterization of Circulating Tumor Cells Using Imaging Flow Cytometry—A Perspective Study
por: Muchlińska, Anna, et al.
Publicado: (2022)

Comparison of three variant callers for human whole genome sequencing
por: Supernat, Anna, et al.
Publicado: (2018)

Longitudinal drug synergy assessment using convolutional neural network image-decoding of glioblastoma single-spheroid cultures
por: Giczewska, Anna, et al.
Publicado: (2023)

Breast cancer circulating tumor cells with mesenchymal features—an unreachable target?
por: Topa, Justyna, et al.
Publicado: (2022)

Tumor Heterogeneity at Protein Level as an Independent Prognostic Factor in Endometrial Cancer()
por: Supernat, Anna, et al.
Publicado: (2014)

Low Tumor-to-Stroma Ratio Reflects Protective Role of Stroma against Prostate Cancer Progression
por: Nastały, Paulina, et al.
Publicado: (2021)

EGFR as a stable marker of prostate cancer dissemination to bones
por: Nastały, Paulina, et al.
Publicado: (2020)

Low Numbers of Vascular Vessels Correlate to Progression in Hormone-Naïve Prostate Carcinomas Undergoing Radical Prostatectomy
por: Smentoch, Julia, et al.
Publicado: (2019)

Improved Characterization of Circulating Tumor Cells and Cancer-Associated Fibroblasts in One-Tube Assay in Breast Cancer Patients Using Imaging Flow Cytometry
por: Muchlińska, Anna, et al.
Publicado: (2023)

Radiotherapy-induced dynamic changes in the lymphocyte-to-monocyte ratio in patients with laryngeal cancer indicate poor prognosis
por: Cichowska-Cwalińska, Natalia, et al.
Publicado: (2023)

ERα36-High Cancer-Associated Fibroblasts as an Unfavorable Factor in Triple-Negative Breast Cancer
por: Nagel, Anna, et al.
Publicado: (2022)

Screening of predicted synergistic multi-target therapies in glioblastoma identifies new treatment strategies
por: Houweling, Megan, et al.
Publicado: (2023)

Pathway-level mutation analysis in primary high-grade serous ovarian cancer and matched brain metastases
por: Duchnowska, Renata, et al.
Publicado: (2022)

Tumor-educated platelet blood tests for Non-Small Cell Lung Cancer detection and management
por: Antunes-Ferreira, Mafalda, et al.
Publicado: (2023)

Tumor-Educated Platelet RNA for the Detection and (Pseudo)progression Monitoring of Glioblastoma
por: Sol, Nik, et al.
Publicado: (2020)

Omics Analysis of Educated Platelets in Cancer and Benign Disease of the Pancreas
por: Mantini, Giulia, et al.
Publicado: (2020)

Prognostic Significance of ESR1 Amplification and ESR1 PvuII, CYP2C19*2, UGT2B15*2 Polymorphisms in Breast Cancer Patients
por: Markiewicz, Aleksandra, et al.
Publicado: (2013)

The Prognostic Significance of Eukaryotic Translation Initiation Factors (eIFs) in Endometrial Cancer
por: Smolle, Maria Anna, et al.
Publicado: (2019)

Spectrum of Epithelial-Mesenchymal Transition Phenotypes in Circulating Tumour Cells from Early Breast Cancer Patients
por: Markiewicz, Aleksandra, et al.
Publicado: (2019)

Interactions between FGFR2 and RSK2—implications for breast cancer prognosis
por: Czaplinska, Dominika, et al.
Publicado: (2016)

Platelet RNA signatures for the detection of cancer
por: Sol, Nik, et al.
Publicado: (2017)

Do platelets LINE up for aging?
por: Schwertz, Hansjörg, et al.
Publicado: (2018)

Aggressive Phenotype of Cells Disseminated via Hematogenous and Lymphatic Route in Breast Cancer Patients
por: Markiewicz, Aleksandra, et al.
Publicado: (2018)

Impact of Escherichia coli K12 and O18:K1 on human platelets: Differential effects on platelet activation, RNAs and proteins
por: Fejes, A. V., et al.
Publicado: (2018)

Liquid biopsies in patients with diffuse glioma
por: Best, Myron G., et al.
Publicado: (2015)

Blood-Based Biomarkers for Glioma in the Context of Gliomagenesis: A Systematic Review
por: Ali, Hamza, et al.
Publicado: (2021)

Johannes Schmiedt (1623–1690)
por: Pekacka-Falkowska, Katarzyna, et al.
Publicado: (2021)

Emerging Evidence for Platelets as Immune and Inflammatory Effector Cells
por: Rondina, Matthew T., et al.
Publicado: (2014)

Stromal expression of ALDH1 in human breast carcinomas indicates reduced tumor progression
por: Bednarz-Knoll, Natalia, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_v1e9g13oe90vjbncughbpp9j0t